17332-12-6

Basic information

• Product Name: 2-BROMO-4-METHOXYPHENOL
• Synonyms: 2-BROMO-4-METHOXYPHENOL
• CAS NO: 17332-12-6
• Molecular Formula: C₇H₇BrO₂
• Molecular Weight: 203.03
• Mol File: 17332-12-6.mol
• Article Data: 14

Chemical Properties

• Melting Point: 47°
• Boiling Point: 281.1 °C at 760 mmHg
• Flash Point: 123.8 °C
• Appearance: /
• Density: 1.585 g/cm³
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 9.49±0.18(Predicted)
• CAS DataBase Reference: 2-BROMO-4-METHOXYPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-4-METHOXYPHENOL(17332-12-6)
• EPA Substance Registry System: 2-BROMO-4-METHOXYPHENOL(17332-12-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 17332-12-6(Hazardous Substances Data)

Usage

General Description

2-Bromo-4-methoxyphenol, also known as 4-Methoxy-2-bromophenol, is an organic chemical compound. It is a phenol derivative with a bromine atom and a methoxy group attached to the phenol ring. This chemical is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a building block in the production of dyes, resins, and other organic compounds. 2-Bromo-4-methoxyphenol is known for its antiseptic properties and is often used in personal care products and as a preservative in various industrial applications. Additionally, it is employed as a reagent in organic synthesis for the preparation of various organic compounds.

Upstream product

• 2746-25-0 p-Methoxybenzyl bromide 
• 17988-20-4 (4-methoxy-benzyl)-trimethyl-silane 
• 67-56-1 methanol 
• 591-20-8 3-Bromophenol 
• 1618092-83-3 3-bromo-4-methoxyphenyl 4-methylbenzenesulfonate 
• 3899-91-0 4-methoxyphenyl p-toluenesulfonate 
• 150-76-5 4-methoxy-phenol 
• 5197-28-4 2-bromo-4-nitroanisole 
• 1200-06-2 4-methoxyphenyl acetate 
• 124764-37-0 3-bromo-4-methoxyphenyl acetate 
• 1523-19-9 4-methoxyphenyl benzoate 
• 60316-51-0 2-bromo-1,1,4,4-tetramethoxycyclohexa-2,5-diene 
• 260558-16-5 3-bromo-5-methoxy phenyl benzoate 
• 578-57-4 2-bromoanisole 

Downstream Products

• 1357091-71-4 cyclohexylcarbamic acid 3′-carbamoyl-6-methoxybiphenyl-3-yl ester 
• 63272-66-2 4-bromo-2-hydroxy-5-methoxybenzaldehyde 
• 1618092-86-6 4-(5,5-dimethyl-1,3-dioxan-2-yl)-5-((2-ethylhexyl)oxy)-2-methoxybenzaldehyde 
• 1618092-87-7 [4-(5,5-dimethyl-1,3-dioxan-2-yl)-5-((2-ethylhexyl)oxy)-2-methoxyphenyl]methanol 
• 1618092-88-8 2-[4-bromomethyl-2-((2-ethylhexyl)oxy)-5-methoxyphenyl]-5,5-dimethyl-1,3-dioxane 
• 1618092-89-9 diethyl 4-(5,5-dimethyl-1,3-dioxan-2-yl)-5-((2-ethylhexyl)oxy)-2-methoxybenzylphosphonate 
• 1618092-90-2 2-[2-((2-ethylhexyl)oxy)-4-iodo-5-methoxyphenyl]-5,5-dimethyl-1,3-dioxane 
• 1618092-91-3 2-((2-ethylhexyl)oxy)-4-iodo-5-methoxybenzaldehyde 
• 1618096-67-5 C₅₀H₇₁IO₇ 
• 1618093-07-4 C₃₃H₄₇IO₅ 
• 1618092-84-4 5-bromo-2-(5,5-dimethyl-1,3-dioxan-2-yl)-4-methoxyphenol 
• 1618092-85-5 2-[4-bromo-2-((2-ethylhexyl)oxy)-5-methoxyphenyl]-5,5-dimethyl-1,3-dioxane 
• 19056-41-8 3-bromo-p-anisidine 
• 158815-52-2 2-bromo-1-methoxy-4-nitrosobenzene 

Relevant articles and documents

Synthetic method 4 - alkoxyphenol compounds

The invention discloses a synthetic method of 4 - alkoxyphenol compounds, and belongs to the field of organic chemical synthesis. The method is as follows: An aryl alkyl ether compound is added to the sealing tube. The catalyst dimerization acetic acid rhodium and the oxidizing agent iodobenzene diethyl ester are added, a solvent trifluoroacetic anhydride is added, and the 4 -alkoxyphenol compound is prepared by heating reaction. To the invention, high regioselectivity direct hydroxylation of the aryl alkyl ether compound is realized, the application range of the substrate is wide, the yield is high, the activity after amplification reaction does not significantly decay, and higher yield is still obtained. The utility model has good practicability and industrial application prospect.

Preparation process of 2-bromo-4-hydroxy anisole

The invention relates to a preparation process of 2-bromo-4-hydroxy anisole. The preparation process comprises the following steps: reacting 4-hydroxy anisole with acetyl chloride in an organic alkalisolution at low temperature to generate 4-acetyl anisol

Direct oxidation of the C(sp2)-C(sp3) bond from benzyltrimethylsilanes to phenols

A novel pathway for direct conversion of benzylsilanes to phenols by oxidation with Na2S2O8 and oxygen is efficiently developed under mild and neutral conditions. The reaction shows good functional group tolerance to afford phenols in moderate yields. The possible mechanism is proposed based on the isotopic labeling trials.