173326-85-7

Basic information

• Product Name: 3,7-dimethyl-9-(2,6,6-trimethylcyclohexene-1-yl)-2E,4E,6Z,8E-nonatetraenoic acid
• Synonyms: 3,7-dimethyl-9-(2,6,6-trimethylcyclohexene-1-yl)-2E,4E,6Z,8E-nonatetraenoic acid
• CAS NO: 173326-85-7
• Molecular Weight: 300.441
• Mol File: 173326-85-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,7-dimethyl-9-(2,6,6-trimethylcyclohexene-1-yl)-2E,4E,6Z,8E-nonatetraenoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,7-dimethyl-9-(2,6,6-trimethylcyclohexene-1-yl)-2E,4E,6Z,8E-nonatetraenoic acid(173326-85-7)
• EPA Substance Registry System: 3,7-dimethyl-9-(2,6,6-trimethylcyclohexene-1-yl)-2E,4E,6Z,8E-nonatetraenoic acid(173326-85-7)

Safety Data

• Hazardous Substances Data: 173326-85-7(Hazardous Substances Data)

Upstream product

• 54168-84-2 trans-β-formyl crotonic acid 

Relevant articles and documents

STEREOSPECIFIC SYNTHESIS PROCESS FOR TRETINOIN COMPOUNDS

A stereospecific synthesis process for tretinoin compounds comprises the following steps: using substituted triphenyl phosphine salt and β-formyl crotonic acid as raw material to carry out WITTIG reaction under the action of alkali; then adjusting the pH of the reaction liquid to 5-10; adding palladium compound or rhodium compound to carry out isomerization directly and obtain tretinoin compounds with desired configuration. The product yield of the process is high and the intermediate product in the reaction dose not need to be separated. The process is easy to operate and can save the production cost and as well is suitable for industrial production.