173327-05-4

Upstream product

• 651321-33-4 (2R,3R,4S)-3,4-Bis-benzyloxy-1-(tert-butyl-dimethyl-silanyloxy)-5,5-bis-ethylsulfanyl-pentan-2-ol 
• 651321-51-6 N-Boc-broussonetine C 
• 220831-03-8 (2R,3R,4R,5R)-3,4-Dihydroxy-2-hydroxymethyl-5-{9-[2-(3-hydroxy-propyl)-[1,3]dioxolan-2-yl]-nonyl}-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 220830-98-8 (3S,4R,5R)-5-(13-Benzyloxy-10-hydroxy-tridecyl)-1-(4-methoxy-benzyl)-3,4-bis-triisopropylsilanyloxy-pyrrolidin-2-one 
• 220831-06-1 (3S,4R,5R)-5-(13-Benzyloxy-10-oxo-tridecyl)-1-(4-methoxy-benzyl)-3,4-bis-triisopropylsilanyloxy-pyrrolidin-2-one 
• 220831-09-4 (2R,3R,4R,5R)-3,4-Bis-benzyloxy-2-{9-[2-(3-benzyloxy-propyl)-[1,3]dioxolan-2-yl]-nonyl}-5-(1,2-dihydroxy-ethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 220831-01-6 [(R)-10-[2-(3-Benzyloxy-propyl)-[1,3]dioxolan-2-yl]-1-((1R,2R,3S)-1,2-bis-benzyloxy-3-hydroxy-pent-4-enyl)-decyl]-carbamic acid tert-butyl ester 
• 220831-10-7 (2R,3R,4R,5R)-3,4-Bis-benzyloxy-2-{9-[2-(3-benzyloxy-propyl)-[1,3]dioxolan-2-yl]-nonyl}-5-hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 220831-02-7 (2R,3R,4R,5R)-3,4-Bis-benzyloxy-2-{9-[2-(3-benzyloxy-propyl)-[1,3]dioxolan-2-yl]-nonyl}-5-vinyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 220831-00-5 (2R,3R,4S)-3,4-Bis-benzyloxy-2-{9-[2-(3-benzyloxy-propyl)-[1,3]dioxolan-2-yl]-nonyl}-5-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 220830-99-9 (3S,4R,5R)-3,4-Bis-benzyloxy-5-(13-benzyloxy-10-oxo-tridecyl)-1-(4-methoxy-benzyl)-pyrrolidin-2-one 
• 220831-05-0 (3S,4R,5R)-5-(10,11-Dihydroxy-undecyl)-1-(4-methoxy-benzyl)-3,4-bis-triisopropylsilanyloxy-pyrrolidin-2-one 
• 220830-97-7 (3S,4R,5R)-1-(4-Methoxy-benzyl)-3,4-bis-triisopropylsilanyloxy-5-undec-10-enyl-pyrrolidin-2-one 
• 220831-08-3 (3S,4R,5R)-3,4-Bis-benzyloxy-5-{9-[2-(3-benzyloxy-propyl)-[1,3]dioxolan-2-yl]-nonyl}-pyrrolidin-2-one 

Relevant academic research and scientific papers

Convergent, stereoselective syntheses of the glycosidase inhibitors broussonetines C, O and P

The first syntheses of the polyhydroxylated alkaloids (iminosugars) broussonetines O and P, glycosidase inhibitors of the pyrrolidine class, have been performed in a convergent, stereocontrolled way from d-serine as the chiral starting material. The synth

An Asymmetric Total Synthesis of Broussonetine C

A total synthesis of (+) Broussonetine C in 16 steps is described from D-arabinose.

First total synthesis of a new tetrasubstituted pyrrolidine alkaloid, broussonetine C

An efficient and stereodefined process is described for the first asymmetric synthesis of a tetrasubstituted pyrrolidine alkaloid, broussoneitne C, as a potent β-galactosidase and β-mannosidase inhibitor by featuring the elaboration through asymmetric deoxgenation of a homochiral C2-imide and stereoselective reduction of its derivative.