17334-09-7

Usage

Uses

Used in Pharmaceutical Development:
1H-Imidazole-2-carboxylic acid methyl ester is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique imidazole ring structure allows it to be a key component in the development of new drugs, potentially contributing to the creation of novel therapeutic agents.
Used in Chemical Reactions:
In the field of organic chemistry, 1H-Imidazole-2-carboxylic acid methyl ester is used as a reactant in a variety of chemical reactions. Its reactivity and functional groups make it a versatile building block for the synthesis of more complex molecules, which can be applied in various industries.
Used in Research Applications:
1H-Imidazole-2-carboxylic acid methyl ester is utilized as a research tool in academic and industrial laboratories. Its properties and reactivity are studied to understand its potential applications and to develop new methodologies for its synthesis and use in various chemical processes.
Used in Industrial Applications:
Although specific uses may vary, 1H-Imidazole-2-carboxylic acid methyl ester is employed in certain industrial processes, where its chemical properties are harnessed to produce desired outcomes or to facilitate specific reactions. Its role in these applications can range from being a catalyst to serving as a key component in the production of other chemicals.

Upstream product

• 186581-53-3 diazomethane 
• 16042-25-4 1H-imidazole-2-carboxylic acid 
• 63678-16-0 N-phenyl-1H-imidazole-2-carboxamide 

Downstream Products

• 1036350-93-2 C₁₄H₁₂F₃N₃O₃ 

Relevant academic research and scientific papers

The Structure of +. and + Ions Formed from Vinylimidazoles, Studied by Collisionally Activated Dissociation Mass Spectrometry

Mass spectra of the three isomeric vinylimidazoles have been compared and the structures of the fragment ions +. and + have been investigated by collisionally activated dissociation mass spectrometry.The greater part of the non-decomposing ions m/z 68 from 2-vinylimidazole and from 2-imidazolecarboxylic acid methyl ester, and a minor part of this ion formed from the free acid, all have the same structure: the imidazole ring system, with hydrogens at both nitrogen atoms but none at C(2).An analogous structure, with an ethynyl group at C(2), is proposed for the m/z 93 ion from 2-vinylimidazole.

5-(1-(IMIDAZOL)METHYL)-3,3-DISUBSTITUTED-2(3H)FURANONE DERIVATIVES

Furanone compounds and compositions having anticholinergic activity are described. The compounds have the formula: STR1 wherein: the dashed line indicates either the 4,5-unsaturated or the 4,5-dihydrofuranone ring;R 1 and R 2 may be the same or different and are hydrogen, thienyl, furanyl, or cycloalkyl (C. sub.3-C 6), benzyl, phenyl, substituted phenyl or substituted benzyl wherein the phenyl or benzyl group may be substituted with halogen, trifluoromethyl, lower alkyl, lower alkoxy or hydroxy;R. sub.3, R 4 and R 5 may be the same or different and are hydrogen, lower alkyl, lower alkyl substituted with a halogen, alkoxy, amino or carboxylic acid group, an alkyl or alkylene bridge between R 4 and R. sub.5 or R 3 and the ring N, trifluoromethyl, nitro, a cycloalkyl group containing 3 to 6 carbons, halogen, benzyl, phenyl, substituted phenyl or substituted benzyl, for which the substituents are the same as those set forth for R 1 and R 2 substituted benzyl or phenyl.R 6 in the dihydrofuranone series is hydrogen or lower alkyl.Also described are the pharmaceutically acceptable quaternary alkyl and acid addition salts of such compounds. The compounds are particularly useful in the treatment of neurogenic bladder disorder and chronic obstructive pulmonary diseases.

Diazafulvenones. Thermal Isomerizations and Eliminations in Alkoxycarbonyl and Anilinocarbonyl Derivatives of Imidazole

4-Carbonyl-4H-imidazole (10) and 2-carbonyl-2H-imidazole (11) are formed by flash vacuum pyrolysis of methyl 4- and 2-imidazolecarboxylates, respectively. 10 and 11 dimerize to diketopiperazines 14 and 16, respectively.The same products are also obtained from 4- and 2-(anilinocarbonyl)imidazoles, respectively.Methyl imidazole-1-carboxylate (4) on pyrolysis gives a ca. 1:1 mixture of the same ketenes 10 and 11, which dimerizes to a 1:2:1 ratio of diketopiperazines 14-16.In contrast, ethyl imidazole-1-carboxylate gave CO2, ethylene, and imidazole as the major products.The pyrolysis reactions were monitored by low-temperature infrared and high-temperature mass spectrometry.