17334-09-7

Basic information

• Product Name: 1H-IMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER
• Synonyms: 1H-IMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER;RARECHEM AL BF 0666;Methyl 1H-iMidazole-2-carboxylate;Methyl 2-IMidazolecarboxylate;Methyl imidazole-2-carboxylate;2-Methoxycarbonylimidazole
• CAS NO: 17334-09-7
• Molecular Formula: C₅H₆N₂O₂
• Molecular Weight: 126.11
• Product Categories: pharmacetical
• Mol File: 17334-09-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 195.5-196.0 °C
• Boiling Point: 262.6±23.0 °C(Predicted)
• Appearance: /
• Density: 1.275±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 11.23±0.10(Predicted)
• CAS DataBase Reference: 1H-IMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-IMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER(17334-09-7)
• EPA Substance Registry System: 1H-IMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER(17334-09-7)

Safety Data

• Hazardous Substances Data: 17334-09-7(Hazardous Substances Data)

Usage

General Description

1H-Imidazole-2-carboxylic acid methyl ester is a chemical compound characterized by its incorporation of an imidazole ring, which is an organic compound with a five-membered ring containing two nitrogen atoms. As a methyl ester derivative of imidazole-2-carboxylic acid, it is useful in a range of chemical reactions and syntheses. Its exact properties can vary depending on its specific structure and the presence of any additional functional groups. This chemical is typically utilized in scientific and industrial applications, especially in the field of pharmaceutical development. Not much information is available on its safety or environmental impact, implying that it may need to be handled with caution.

Upstream product

• 186581-53-3 diazomethane 
• 16042-25-4 1H-imidazole-2-carboxylic acid 
• 63678-16-0 N-phenyl-1H-imidazole-2-carboxamide 

Downstream Products

• 1036350-93-2 C₁₄H₁₂F₃N₃O₃ 

Relevant articles and documents

The Structure of +. and + Ions Formed from Vinylimidazoles, Studied by Collisionally Activated Dissociation Mass Spectrometry

Mass spectra of the three isomeric vinylimidazoles have been compared and the structures of the fragment ions +. and + have been investigated by collisionally activated dissociation mass spectrometry.The greater part of the non-decomposing ions m/z 68 from 2-vinylimidazole and from 2-imidazolecarboxylic acid methyl ester, and a minor part of this ion formed from the free acid, all have the same structure: the imidazole ring system, with hydrogens at both nitrogen atoms but none at C(2).An analogous structure, with an ethynyl group at C(2), is proposed for the m/z 93 ion from 2-vinylimidazole.

Diazafulvenones. Thermal Isomerizations and Eliminations in Alkoxycarbonyl and Anilinocarbonyl Derivatives of Imidazole

4-Carbonyl-4H-imidazole (10) and 2-carbonyl-2H-imidazole (11) are formed by flash vacuum pyrolysis of methyl 4- and 2-imidazolecarboxylates, respectively. 10 and 11 dimerize to diketopiperazines 14 and 16, respectively.The same products are also obtained from 4- and 2-(anilinocarbonyl)imidazoles, respectively.Methyl imidazole-1-carboxylate (4) on pyrolysis gives a ca. 1:1 mixture of the same ketenes 10 and 11, which dimerizes to a 1:2:1 ratio of diketopiperazines 14-16.In contrast, ethyl imidazole-1-carboxylate gave CO2, ethylene, and imidazole as the major products.The pyrolysis reactions were monitored by low-temperature infrared and high-temperature mass spectrometry.