173406-18-3

Usage

Uses

Used in Pharmaceutical Industry:
N-(2-phenylethyl)-3-aminopropionic acid is used as a nootropic for enhancing cognitive function and improving mental performance.
Used in Mental Health Applications:
N-(2-phenylethyl)-3-aminopropionic acid is used as an anxiolytic to alleviate anxiety and stress, providing a calming effect to those suffering from anxiety disorders.
Used in Sleep Aid Formulations:
N-(2-phenylethyl)-3-aminopropionic acid is used as a sleep aid to improve sleep quality and duration for individuals experiencing insomnia or other sleep disturbances.
Used in Recreational Drug Culture:
Although not recommended due to health risks, N-(2-phenylethyl)-3-aminopropionic acid has been used recreationally for its euphoric and relaxing effects. However, its addictive potential and associated withdrawal symptoms have led to regulatory actions limiting its availability in some regions.

Upstream product

• 40871-01-0 methyl 3-propionate 
• 64-04-0 phenethylamine 

Relevant academic research and scientific papers

N-, α-, and β-substituted 3-aminopropionic acids: Design, syntheses and antiseizure activities

A treatment for epilepsy is proposed based on analogues of 3-aminopropionic acid (β-alanine), a putative neurotransmitter in the central nervous system (CNS). A model three point pharmacophore was proposed based on modelling data obtained from the study of antagonists for both the glial γ-aminobutyric acid (GABA)-uptake site and the glycine co-agonist site of N-methyl-D-aspartate (NMDA) receptor. Three series of 3-aminopropionic acids containing, N-, α-, and β-substituents, were designed and synthesized to probe the position and the size of a lipophilic binding pocket within the proposed pharmacophore. These analogues were tested in vivo for both their antiseizure activities and their neurologic toxicities. Among the fourteen novel 3-aminopropionic acids synthesized, eight were found to have promising antiseizure activity. This study shows that substitution on the N-terminus confers the greatest antiseizure activity, particularly against pilocarpine-induced seizures.

Anti-epileptogenic agents

Methods and compounds useful for the inhibition of convulsive disorders, including epilepsy, are disclosed. The methods and compounds of the invention inhibit or prevent ictogenesis and epileptogenesis. Methods for preparing the compounds of the invention