173417-34-0

Basic information

• Product Name: DIMETHYL 2-(3-NITRO-2-PYRIDYL)MALONATE
• Synonyms: DIMETHYL 2-(3-NITRO-2-PYRIDYL)MALONATE;Dimethyl 2-(3-nitropyridin-2-yl)malonate;DIMETHYL (3-NITROPYRID-2-YL)MALONATE
• CAS NO: 173417-34-0
• Molecular Formula: C10H10N2O6
• Molecular Weight: 254.2
• Mol File: 173417-34-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 366.9°C at 760 mmHg
• Flash Point: 175.7°C
• Appearance: /
• Density: 1.377g/cm³
• Vapor Pressure: 1.41E-05mmHg at 25°C
• Refractive Index: 1.539
• Storage Temp.: Room temperature.
• CAS DataBase Reference: DIMETHYL 2-(3-NITRO-2-PYRIDYL)MALONATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL 2-(3-NITRO-2-PYRIDYL)MALONATE(173417-34-0)
• EPA Substance Registry System: DIMETHYL 2-(3-NITRO-2-PYRIDYL)MALONATE(173417-34-0)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 173417-34-0(Hazardous Substances Data)

Usage

General Description

DIMETHYL 2-(3-NITRO-2-PYRIDYL)MALONATE is a chemical compound with the molecular formula C9H8N2O6. It is an ester derived from malonic acid and 3-nitro-2-pyridine carboxylic acid. DIMETHYL 2-(3-NITRO-2-PYRIDYL)MALONATE is commonly used in organic synthesis as a reagent for the preparation of various pharmaceuticals and agricultural chemicals. It is a pale yellow crystalline solid with a melting point of 78-80°C. DIMETHYL 2-(3-NITRO-2-PYRIDYL)MALONATE is also considered a potential precursor for the synthesis of other organic compounds due to its versatile chemical properties. However, it is important to handle this chemical with care as it is toxic if ingested or inhaled, and can cause skin and eye irritation.

InChI:InChI=1/C10H10N2O6/c1-17-9(13)7(10(14)18-2)8-6(12(15)16)4-3-5-11-8/h3-5,7H,1-2H3

Upstream product

• 5470-18-8 2-Chloro-3-nitropyridine 
• 60-29-7 diethyl ether 
• 108-59-8 malonic acid dimethyl ester 

Downstream Products

• 1373232-56-4 C₁₀H₁₂N₂O₄ 
• 65156-92-5 2-(3-nitro-2-pyridinyl)-N,N-dimethyletheneamine 
• 65156-92-5 (E)-N,N-dimethyl-2-(3-nitropyridin-2-yl)ethenamine 

Relevant articles and documents

3-(INDOLYL)-OR 3-(AZAINDOLYL)- 4-ARYLMALEIMIDE DERIVATIVES FOR USE IN THE TREATMENT OF COLON AND GASTRIC ADENOCARZINOMA

no abstract published

3-(indolyl)- or 3-(azaindolyl)-4-arylmaleimide derivatives for use in the treatment of colon and gastric adenocarcinoma

The present invention relates to the use of a compound of formula (I) wherein R1, and R3 are as defined in the description and R2 is a phenyl group which is substituted with 2 or 3 C1-G6 alkoxy groups, or a physiologically acceptable salt thereof, or a solvate of the compound of formula (I) or of the salt thereof, for treatment of colorectal or gastric adenocarcinoma.

Diphosphine-catalyzed mixed double-michael reaction: A unified synthesis of lndolines, Dihydropyrrolopyridines, Benzimidazolines, Tetrahydroquinolines, Tetrahydroisoquinolines, Dihydrobenzo-1,4-oxazines, and Dihydrobenzo-3,1- oxazines

(Figure Presented) Seven different types of benzannulated N-heterocycles-indolines, dihydropyrrolopyridlnes, benzimidazolines, dihydrobenzo-3,1-oxazines, benzomorpholines, tetrahydroquinolines, and tetrahydroisoquinolines-can be obtained from simple dinuc