173418-76-3Relevant academic research and scientific papers
An efficient method to construct the A,B-rings component toward total syntheses of phycocyanobilin and its derivative as a photoprobe
Jayasundera, Krishanthi Padmarani,Kinoshita, Hideki,Inomata, Katsuhiko
, p. 497 - 500 (2000)
Total syntheses of physocyanobilin and its derivative bearing a photoreactive group at the D-ring accomplished by developing a new and efficient method for the construction of A,B-rings component, which consists of the Wittig-type new coupling reaction of 4-(1-methoxyethyl or 1- tosylethyl)-3-methyl-5-tosyl-1,5-dihydro-2H-pyrrol-2-one and a 2-formyl pyrrole derivative in the presence of (n)Bu3P and a base, followed by reduction with aluminum amalgam and a subsequent acid or base treatment.
