173419-94-8Relevant articles and documents
Direct enantioselective: C -acylation for the construction of a quaternary stereocenter catalyzed by a chiral bicyclic imidazole
Wang, Mo,Zhang, Xiao,Ling, Zheng,Zhang, Zhenfeng,Zhang, Wanbin
supporting information, p. 1381 - 1384 (2017/02/05)
A direct enantioselective C-acylation of 3-substituted benzofuran-2(3H)-ones (with up to 97% ee) was developed using a chiral bicyclic imidazole catalyst OAc-DPI and an achiral tertiary amine additive DIPEA. The reaction mechanism for the direct C-acylation has been investigated using both experimental and theoretical studies.