173440-82-9

Upstream product

• 1152-61-0 N-Cbz-L-Asp 
• 23632-66-8 (4S)-3-benzyloxycarbonyl-4-carboxymethyl-1,3-oxazolidin-5-one 

Downstream Products

• 173440-83-0 (4S)-3-(benzyloxycarbonyl)-4-(2-triethylsiloxyethyl)-1,3-oxazolidin-5-one 
• 35677-89-5 benzyl (3S)-2-oxotetrahydro-3-furanylcarbamate 
• 173440-93-2 3-benzyloxycarbonylamino-1-butyl-3-(3-phthalimidopropyl)-2-pyrrolidinone 
• 173440-95-4 3-benzyloxycarbonylamino-1-butyl-3-(3-tert-butoxycarbonylaminopropyl)-2-pyrrolidinone 
• 173440-85-2 3-(benzyloxycarbonyl)-4-(2-propenyl)-4-(2-triethylsiloxyethyl)-1,3-oxazolidin-5-one 
• 173440-91-0 3-benzyloxycarbonylamino-1-butyl-3-(3-hydroxypropyl)-2-pyrrolidinone 
• 173440-89-6 3-benzyloxycarbonylamino-1-butyl-3-(2-propenyl)-2-pyrrolidinone 
• 173440-87-4 3-(benzyloxycarbonyl)-4-(2-propenyl)-4-(2-hydroxyethyl)-1,3-oxazolidin-5-one 

Relevant academic research and scientific papers

A microwave-assisted synthesis of (S)-N-protected homoserine γ-lactones from l-aspartic acid

A three-pot preparation of (S)-N-protected homoserine γ-lactones is presented. Conversion of N-protected l-aspartic acid to an oxazolidinone is followed by selective reduction/acid-catalyzed cyclization to deliver the lactones. Microwave irradiation proved valuable for improving the latter reaction steps in some cases.

Lactam-conformationally restricted analogs of N(α)-arylsulfonyl arginine amide: Design, synthesis and inhibitory activity toward thrombin and related enzymes

Three new lactam-conformationally restricted arginine derivatives, 1- butyl-3-(6,7-dimethoxy-2-naphthylsulfonyl)-3-(3-guanidinopropyl)-substituted γ-, δ-, and ε-lactams (2-4), were synthesized on the basis of backbone modification of the lead structure, 6