173442-71-2

Upstream product

• 6940-78-9 4-chlorobutyl bromide 
• 154810-51-2 4-benzyloxy-5-methoxyindole-3-carbaldehyde 

Downstream Products

• 173442-67-6 8-Benzyloxy-2-methoxy-6,7,8,9-tetrahydropyrido<1,2-a>indole-10-carbaldehyde 
• 173442-64-3 4-Benzyloxy-1-(4-iodobutyl)-5-methoxyindole-3-carbaldehyde 

Relevant academic research and scientific papers

Synthesis of 1,2-fused indoles by radical cyclisation

Treatment of the 1-(ω-iodoalkyl)indole-3-carboxaldehydes 8-13 with tributyltin hydride and AIBN results in radical cyclisation with oxidation to given the 1,2-fused indoles 14-19.

Synthesis of 1,2-fused indoles by radical cyclisation

Treatment of the 1-(ω-iodoalkyl)indole-3-carbaldehydes 8-13 with tributyltin hydride and AIBN results in radical cyclisation to give the 1,2-fused indoles 14-19 containing five-, six- and seven-membered rings. The tetrahydropyridoindole 18 is converted into the indolequinone 23.