173459-74-0Relevant articles and documents
1,4-Benzodiazepine peripheral cholecystokinin (CCK-A) receptor agonists
Sherrill, Ronald G.,Berman, Judd M.,Birkemo, Lawrence,Croom, Dallas K.,Dezube, Milana,Ervin, Gregory N.,Grizzle, Mary K.,James, Michael K.,Johnson, Michael F.,Queen, Kennedy L.,Rimele, Thomas J.,Vanmiddlesworth, Frank,Sugg, Elizabeth E.
, p. 1145 - 1148 (2007/10/03)
A series of 1,4-benzodiazepines, N-1-substituted with an N-isopropyl-N-phenylacetamide moiety, was synthesized and screened for CCK-A agonist activity. In vitro agonist activity on isolated guinea pig gallbladder along with in vivo induction of satiety fo