173482-91-2

Upstream product

• 107-86-8 3,3-dimethyl acrylaldehyde 
• 173482-90-1 2-bromo-6,6-dimethyl-3-ethoxycyclohex-2-en-1-one 
• 62952-32-3 3-ethoxy-6,6-dimethylcyclohex-2-en-1-one 

Downstream Products

• 173482-93-4 4,4-dimethyl-3-hydroxymethyl-2-(1-methoxymethoxy-3-methylbut-2-en-1-yl)-cyclohex-2-en-1-one 
• 173482-92-3 4,4-dimethyl-1-ethoxy-2-(1-methoxymethoxy-3-methylbut-2-en-1-yl)-3-methylenecyclohex-1-ene 
• 173482-98-9 6,6-dimethyl-3-ethoxy-2-(1-methoxymethoxy-3-methylbut-2-en-1-yl)-cyclohex-2-en-1-one 

Relevant academic research and scientific papers

Synthetic studies towards phomactin A. Concise synthesis of the novel tricyclic furanochroman system

A concise synthesis of the tricyclic furanochroman unit 2 found in the unusual PAF antagonist phomactin A 1 is described. The synthesis is based on elaboration of the novel dihydrofuran enol ether 3 as key intermediate via the iodopyran 6 or the dihydrofu

Synthetic studies towards the phomactins. Concise syntheses of the tricyclic furanochroman and the oxygenated bicyclo[9.3.1]pentadecane ring systems in phomactin A.

A concise synthesis of the tricyclic furanochroman unit 3 found in the PAF antagonist phomactin A (1) isolated from the marine fungus Phoma sp., is described. In complementary studies, a variety of synthetic routes towards the bicyclo[9.3.1]pentadecane ring system 4 in phomactin A were explored. These studies culminated in a synthesis of the substituted ring system 79 containing all the carbon atoms and all the necessary oxygen centres for elaboration to phomactin A itself.