17349-94-9

Basic information

• Product Name: 2-benzhydryloxyethanamine
• Synonyms: 2-(Benzhydryloxy)ethanamine
• CAS NO: 17349-94-9
• Molecular Formula: C₁₅H₁₇NO
• Molecular Weight: 227.3016
• Product Categories: Amines, Aromatics
• Mol File: 17349-94-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 343.9°Cat760mmHg
• Flash Point: 137.6°C
• Appearance: /
• Density: 1.068g/cm³
• Vapor Pressure: 6.84E-05mmHg at 25°C
• Refractive Index: 1.573
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 2-benzhydryloxyethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzhydryloxyethanamine(17349-94-9)
• EPA Substance Registry System: 2-benzhydryloxyethanamine(17349-94-9)

Safety Data

• Hazardous Substances Data: 17349-94-9(Hazardous Substances Data)

Usage

Uses

2-(Diphenylmethoxy)-N-ethylamine (cas# 17349-94-9) is a compound useful in organic synthesis.

InChI:InChI=1/C15H17NO/c16-11-12-17-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10,15H,11-12,16H2

Upstream product

• 58-73-1 2-diphenylmethoxy-N,N-dimethylethanamine 
• 91-01-0 1,1-Diphenylmethanol 
• 101620-15-9 2-(2-(benzhydryloxy)ethyl)isoindoline-1,3-dione 
• 6305-20-0 2-bromoethyl benzhydryl ether 

Downstream Products

• 525-01-9 4-<2-(benzhydryloxy)ethyl>morpholine 
• 115129-59-4 N-<2-(diphenylmethoxy)ethyl>-N'-<3-(imidazol-4-yl)propyl>guanidine 
• 118554-17-9 N-<2-(diphenylmethoxy)ethyl>-S-<2-(imidazol-4-yl)ethyl>isothiourea 
• 776256-78-1 1-(2-Benzhydryloxy-ethyl)-2-methyl-isothiourea 
• 115129-84-5 N-<2-(diphenylmethoxy)ethyl>thiourea 
• 16136-32-6 N-(2-Benzhydryloxy-aethyl)-guanidin 
• 65236-18-2 (2-Benzhydryloxy-ethyl)-[2-(3,4-dichloro-phenoxy)-1-methyl-ethyl]-amine 
• 62099-00-7 N-{4-[2-(2-Benzhydryloxy-ethylamino)-propoxy]-phenyl}-acetamide 
• 114667-28-6 1-(2-Benzhydryloxy-ethyl)-3-benzoyl-thiourea 
• 62099-06-3 [2-(2-Allyl-phenoxy)-1-methyl-ethyl]-(2-benzhydryloxy-ethyl)-amine 

Relevant articles and documents

Bacterial Biosynthetic P450 Enzyme PikCD50N: A Potential Biocatalyst for the Preparation of Human Drug Metabolites

Human drug metabolites (HDMs) are important chemicals widely used in drug-related studies. However, acquiring these enzyme-derived and regio-/stereo-selectively modified compounds through chemical approaches is complicated. PikC is a biosynthetic P450 enz

Skin care

PROBLEM TO BE SOLVED: To provide a skin care preparation suitable for a cosmetic (provided that quasi drugs are included) or the like, for detail, a skin care preparation having whitening effects, particularly preventive or improving effects against pigme

Design, synthesis and pharmacological characterization of analogs of 2-aminoethyl diphenylborinate (2-APB), a known store-operated calcium channel blocker, for inhibition of TRPV6-mediated calcium transport

2-Aminoethyl diphenylborinate (2-APB) is a known modulator of the IP 3 receptor, the calcium ATPase SERCA, the calcium release-activated calcium channel Orai and TRP channels. More recently, it was shown that 2-APB is an efficient inhibitor of the epithelial calcium channel TRPV6 which is overexpressed in prostate cancer. We have conducted a structure-activity relationship study of 2-APB congeners to understand their inhibitory mode of action on TRPV6. Whereas modifying the aminoethyl moiety did not significantly change TRPV6 inhibition, substitution of the phenyl rings of 2-APB did. Our data show that the diaryl borinate moiety is required for biological activity and that the substitution pattern of the aryl rings can influence TRPV6 versus SOCE inhibition. We have also discovered that 2-APB is hydrolyzed and transesterified within minutes in solution.