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HMN 176 is a novel small molecule inhibitor of the phosphatidylinositol 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) pathways, which are crucial in cancer cell growth and survival. This chemical compound has demonstrated potential in the treatment of various types of cancer, including prostate, breast, and lung cancer, both in vitro and in vivo. Its ability to inhibit cancer cell growth, combined with its synergistic effects with other anti-cancer agents, makes HMN 176 a promising candidate for combination therapy. Furthermore, its favorable pharmacokinetic and safety profiles in preclinical studies support its potential as a therapeutic agent for cancer treatment.

173529-10-7

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173529-10-7 Usage

Uses

Used in Oncology:
HMN 176 is used as an anti-cancer agent for its ability to inhibit the growth of various types of cancer cells, such as prostate, breast, and lung cancer. It targets the PI3K and mTOR pathways, which play a critical role in cancer cell growth and survival.
Used in Combination Therapy:
HMN 176 is used in combination with other anti-cancer agents to enhance the therapeutic effects and overcome drug resistance in cancer treatment. Its synergistic effects with other agents make it a promising candidate for combination therapy.
Used in Preclinical Research:
HMN 176 is used in preclinical studies to evaluate its pharmacokinetic and safety profiles, providing valuable information for its potential development as a therapeutic agent for cancer treatment.
Used in Drug Development:
HMN 176 is used in the development of novel cancer treatments, leveraging its inhibitory effects on the PI3K and mTOR pathways and its potential for combination therapy with other anti-cancer agents.

Check Digit Verification of cas no

The CAS Registry Mumber 173529-10-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,3,5,2 and 9 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 173529-10:
(8*1)+(7*7)+(6*3)+(5*5)+(4*2)+(3*9)+(2*1)+(1*0)=137
137 % 10 = 7
So 173529-10-7 is a valid CAS Registry Number.

173529-10-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (NE)-N-[(6E)-6-[2-(1-hydroxypyridin-4-ylidene)ethylidene]cyclohexa-2,4-dien-1-ylidene]-4-methoxybenzenesulfonamide

1.2 Other means of identification

Product number -
Other names HMN-176

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:173529-10-7 SDS

173529-10-7Upstream product

173529-10-7Downstream Products

173529-10-7Relevant academic research and scientific papers

REMEDIAL AGENT FOR CHRONIC ARTICULAR RHEUMATISM

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, (2008/06/13)

The present invention relates to an excellent remedial agent for chronic rheumatoid arthritis, comprising an aminostilbazole, derivative represented by the following formula [1] or a salt thereof as an active ingredient:A-B-D-E Wherein A represents hetero

Aminostilbazole derivative and medicine

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, (2008/06/13)

The invention relates to an aminostilbazole derivative of the following formula or a hydrate thereof, and a salt thereof. STR1 wherein R1 and R2 each represents hydrogen etc.; R3, R4, R13, and R14 each represents hydrogen, C1-3 acyl, halogen, hydroxy etc.; R5 represents hydrogen or hydroxy-substituted C1-3 alkyl etc.; R6 represents benzenesulfonyl substituted by C1-3 alkoxy etc.; ring Y represents phenyl etc.; ring Z represents 4-pyridyl, its oxide etc. The compound is useful or the treatment of various malignant tumors.

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