17356-25-1Relevant articles and documents
Rh-Catalyzed Asymmetric Hydrogenation of β-Branched Enol Esters for the Synthesis of β-Chiral Primary Alcohols
Liu, Chong,Yuan, Jing,Zhang, Jian,Wang, Zhihui,Zhang, Zhenfeng,Zhang, Wanbin
, p. 108 - 111 (2018)
An asymmetric hydrogenation of β-branched enol esters has been developed for the first time, providing a new route for the synthesis of β-chiral primary alcohols. Using a (S)-SKP-Rh complex bearing a large bite angle and enol ester substrates possessing an O-fomyl directing group, the desired products were obtained in quantitative yields and with excellent enantioselectivities.
