17357-25-4Relevant academic research and scientific papers
TMS·OTf-Catalyzed α-bromination of carbonyl compounds by N-bromosuccinimide
Guha, Samar Kumar,Wu, Bo,Kim, Beom Soo,Baik, Woonphil,Koo, Sangho
, p. 291 - 293 (2007/10/03)
Various carbonyl compounds undergo α-bromination reaction under a mild and practical condition utilizing N-bromosuccinimide (NBS), catalyzed by trimethylsilyl trifluoromethanesulfonate (TMS·OTf). This method is also effective for the side-chain bromination of heteroaromatic carbonyl compounds without the ring brominations.
An easy synthesis of 2-haloacetylfurans and -thiophenes
Dubac,Gaset,Maraval
, p. 11 - 16 (2007/10/02)
The 2-chloro (or bromo)acetylfurans and -thiophenes were selectively synthesized with preservation of the heteroaromatic cycle from enoxysilane forms of 2-acetylfurane and -thiophene.
MAGNESIUM CHLORIDE DIRECTED ALDOL AND BROMINATION OF 2-ACETYLFURAN
Mansour, Tarek S.
, p. 727 - 734 (2007/10/02)
Reaction of 2-acetylfuran with diisopropylethylamine and magnesium chloride followed by bromination gave 1,3-difuryl-3-hydroxy-1-butanone and 1,3-difuryl-4-bromo-3-hydroxy-1-butanone.Under similar conditions 2-acetylthiophene failed to react.
