17358-66-6 Usage
Uses
Used in Medicinal Chemistry:
1-[(4-Methylphenyl)sulfonyl]azetidin-3-yl 4-Methylbenzenesulfonate is used as a chemical compound in medicinal chemistry for the development of new drugs. Its unique structure and potential pharmacological properties make it a promising candidate for the creation of novel therapeutic agents.
Used in Organic Synthesis:
In the field of organic synthesis, 1-[(4-Methylphenyl)sulfonyl]azetidin-3-yl 4-Methylbenzenesulfonate is used as a reagent for the preparation of other chemical compounds with similar structural features. Its versatility in chemical reactions allows for the synthesis of a variety of related compounds, expanding the scope of available chemical entities for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 17358-66-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,5 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 17358-66:
(7*1)+(6*7)+(5*3)+(4*5)+(3*8)+(2*6)+(1*6)=126
126 % 10 = 6
So 17358-66-6 is a valid CAS Registry Number.
InChI:InChI=1/C17H19NO5S2/c1-13-3-7-16(8-4-13)24(19,20)18-11-15(12-18)23-25(21,22)17-9-5-14(2)6-10-17/h3-10,15H,11-12H2,1-2H3
17358-66-6Relevant academic research and scientific papers
Synthesis of azetidine derivatives using 1-azabicyclo[1.1.0]butane
Hayashi, Kazuhiko,Hiki, Shinsuke,Kumagai, Toshio,Nagao, Yoshimitsu
, p. 433 - 442 (2007/10/03)
A THF solution of 1-azabicyclo[1.1.0]butane (2), obtained from 2,3-dibromopropylamine hydrobromide (1), was treated with HC1-EtOH, 48% HBr, ClCO2Et, Ts2O, HCO2H-2.7N HCl-MeOH, or Ac2O- 3N HCl to give the corresponding 3-monosubstituted and 1,3-disubstituted azetidine derivatives (3-7). Similar treatment of 2 with AcSH afforded 1-acetyl-3-acetylthioazetidine (8), which was converted to 1-(1,3-thiazolidin-2-yl)azetidine-3-thiol hydrochloride (10). The compound (2) and various bromides were heated to furnish 3-bromoazetidine derivatives (12b,c,e,f) and/or N,N-disubstituted 2,3-dibromopropylamines (13a, c-f). The reaction of 2 with benzoyl peroxide or N-bromosuccinimide gave each corresponding 1,3-disubustituted azetidine derivative (14 or 15).
