1736-80-7

Basic information

• Product Name: 2-(2-CHLORO-4-FLUOROPHENOXY)ACETOHYDRAZIDE
• Synonyms: 2-(2-CHLORO-4-FLUOROPHENOXY)ACETOHYDRAZIDE;2-(2-chloro-4-fluorophenoxy)acetohydrazide(SALTDATA: FREE);2-(2-chloro-4-fluoro-phenoxy)ethanehydrazide
• CAS NO: 1736-80-7
• Molecular Formula: C₈H₈ClFN₂O₂
• Molecular Weight: 218.62
• Mol File: 1736-80-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 429.1°C at 760 mmHg
• Flash Point: 213.3°C
• Appearance: /
• Density: 1.403g/cm³
• Vapor Pressure: 1.44E-07mmHg at 25°C
• Refractive Index: 1.55
• PKA: 12.01±0.35(Predicted)
• CAS DataBase Reference: 2-(2-CHLORO-4-FLUOROPHENOXY)ACETOHYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-CHLORO-4-FLUOROPHENOXY)ACETOHYDRAZIDE(1736-80-7)
• EPA Substance Registry System: 2-(2-CHLORO-4-FLUOROPHENOXY)ACETOHYDRAZIDE(1736-80-7)

Safety Data

• Hazardous Substances Data: 1736-80-7(Hazardous Substances Data)

Usage

General Description

2-(2-chloro-4-fluorophenoxy)acetohydrazide is a chemical compound with the molecular formula C10H10ClFN2O2. It is a hydrazide derivative with a phenoxy group and a chloro-fluoro substituent. 2-(2-CHLORO-4-FLUOROPHENOXY)ACETOHYDRAZIDE is used as a reagent in organic synthesis and as an intermediate in the production of pharmaceuticals and agrochemicals. It has potential applications in the development of new drugs with anti-inflammatory, antiviral, and anticancer properties. Additionally, it may also be used in the formulation of herbicides and pesticides for agricultural purposes. Overall, 2-(2-chloro-4-fluorophenoxy)acetohydrazide has diverse applications in the pharmaceutical and agricultural industries, making it a valuable compound in chemical synthesis and drug discovery.

InChI:InChI=1/C8H8ClFN2O2/c9-6-3-5(10)1-2-7(6)14-4-8(13)12-11/h1-3H,4,11H2,(H,12,13)

Upstream product

• 1716-85-4 ethyl [(2-chloro-4-fluorophenyl)oxy]acetate 
• 1996-41-4 2-chloro-4-fluorophenol 

Relevant articles and documents

Synthesis and larvicidal activity of 1,3,4-oxadiazole derivatives containing a 3-chloropyridin-2-yl-1H-pyrazole scaffold

Abstract: A new series of 1,3,4-oxadiazole derivatives with a 3-chloropyridin-2-yl-1H-pyrazole moiety was designed, synthesized, and characterized. The results of bioassay against Helicoverpa armigera and Plutella xylostella indicated that some of the synthesized compounds showed remarkable larvicidal activity. In particular, the LC50 values of the most active compounds against P. xylostella were 46.5, 23.9, and 13.9?mg/dm3, and against Helicoverpa armigera were 88.3 and 69.5?mg/dm3, the latter being slightly better than commercial chlorpyrifos (LC50 103.77?mg/dm3). Preliminary SAR was also discussed. Graphical abstract: [Figure not available: see fulltext.].