173601-36-0Relevant articles and documents
Evolution of anti-HIV drug candidates. Part 2: Diaryltriazine (DATA) analogues
Ludovici, Donald W.,Kavash, Robert W.,Kukla, Michael J.,Ho, Chih Y.,Ye, Hong,De Corte, Bart L.,Andries, Koen,De Bethune, Marie-Pierre,Azijn, Hilde,Pauwels, Rudi,Moereels, Henry E.L.,Heeres, Jan,Koymans, Lucien M.H.,De Jonge, Marc R.,Van Aken, Koen J.A.,Daeyaert, Frederik F.D.,J. Lewi, Paul,Das, Kalyan,Arnold, Edward,Janssen, Paul A.J.
, p. 2229 - 2234 (2007/10/03)
A synthesis program directed toward improving the stability of imidoyl thiourea based non-nucleoside reverse transcriptase inhibitors (NNRTIs) led to the discovery of diaryltriazines (DATAs), a new class of potent NNRTIs. The synthesis and anti-HIV struct