173605-16-8Relevant academic research and scientific papers
STUDIES WITH POLYFUNCTIONALLY SUBSTITUTED HETEROAROMATICS: NEW ROUTES FOR SYNTHESIS OF BENZOAZINES
Negm, Abdalla M.,El-Aal, Fatma Abd El-Maksoud Abd,Hafez, Ebtisam A.,Elnagdi, Mohamed H.,Mostafa, Yasser M. N.
, p. 1 - 8 (2007/10/03)
Pyridazine (I) reacts with dimethyl acetylenedicarboxylate and with N-phenyl-maleimide yielding phthalazine (II) and pyrrolophthalazine (III), respectively.Pyridine IV reacts with benzylidene malononitrile to give compound VI.Compounds VIa-c could be successfully converted into the isoquinolines XIa-c on treatment with acrylonitrile.In contrast to the behavior of arylidene malononitrile, compound IV react with N-phenylmaleimide to yield the pyrroloisoquinoline XIII.Similarly, the reaction of compound IV with each of tetracyanoethylene and dimethyl acetylenecarboxylate gave compounds XIV and XV respectively.Key words: Phthalazine, pyrrolophthalazine, isoquinoline, pyrroloisoquinoline, pyridothienopyridine.
