173692-85-8

Basic information

• Product Name: 4H-1,2,4-Triazole-4-propanenitrile(9CI)
• Synonyms: 4H-1,2,4-Triazole-4-propanenitrile(9CI);3-(4H-1,2,4-Triazol-4-yl)propanenitrile
• CAS NO: 173692-85-8
• Molecular Formula: C5H6N4
• Molecular Weight: 122.13
• Product Categories: AMINETERTIARY
• Mol File: 173692-85-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: 4H-1,2,4-Triazole-4-propanenitrile(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,2,4-Triazole-4-propanenitrile(9CI)(173692-85-8)
• EPA Substance Registry System: 4H-1,2,4-Triazole-4-propanenitrile(9CI)(173692-85-8)

Safety Data

• Hazardous Substances Data: 173692-85-8(Hazardous Substances Data)

Usage

Uses

3-(4H-1,2,4-Triazol-4-yl)propanenitrile is an impurity in the synthesis of Iso Fluconazole (Fluconazole EP Impurity A) is an impurity of Fluconazole (F421000). Fluconazole USP impurity A.

Upstream product

• 288-88-0 1,2,4-Triazole 
• 107-13-1 acrylonitrile 

Relevant articles and documents

Double-triazole substituted ethoxy compound and its preparation method and application

The invention discloses a double-triazole substituted ethoxy benzene compound and a preparation method and application thereof. The organic compound is prepared by conducting reflux reaction on 1,4-bis (bromomethyl)-2,5-diethoxy benzene with 3-(1H-1,2,4-triazole-1-yl) propionitrile in acetonitrile, and then conducting basic hydrolysis. The preparation method of the present invention has the characteristics of simple operation, low production cost and little environmental pollution, and is applicable to large scale industrialization production. The compound prepared by the invention can be applied to the research on bactericide. The experimental results confirm that the double-triazole substituted ethoxy benzene compound has certain sterilization activity on Escherichia coli and Staphylococcus aureus, especially significant bactericidal activity against Staphylococcus aureus.