17370-06-8

Upstream product

• 6621-75-6 2,4-dimethylthiosemicarbazide 
• 78-39-7 Triethyl orthoacetate 

Downstream Products

• 92593-47-0 C₁₃H₁₈N₃O₂S⁽¹⁺⁾*BF₄^(1-) 
• 88305-31-1 Toluene-4-sulfonate3-(2,5-dihydroxy-3,4-dimethyl-phenylsulfanyl)-1,4,5-trimethyl-4H-[1,2,4]triazol-1-ium; 
• 88305-25-3 Toluene-4-sulfonate3-(3,6-dihydroxy-2,4-dimethyl-phenylsulfanyl)-1,4,5-trimethyl-4H-[1,2,4]triazol-1-ium; 
• 88305-34-4 Toluene-4-sulfonate3-(2,5-dihydroxy-3,6-dimethyl-phenylsulfanyl)-1,4,5-trimethyl-4H-[1,2,4]triazol-1-ium; 
• 88305-52-6 Toluene-4-sulfonate3-(2,5-dihydroxy-3-methoxy-phenylsulfanyl)-1,4,5-trimethyl-4H-[1,2,4]triazol-1-ium; 
• 88305-56-0 Toluene-4-sulfonate3-(4-benzenesulfonylamino-1-hydroxy-naphthalen-2-ylsulfanyl)-1,4,5-trimethyl-4H-[1,2,4]triazol-1-ium; 
• 92593-52-7 Toluene-4-sulfonate3-(5,8-dihydroxy-1,2,3,4-tetrahydro-1,4-methano-naphthalen-6-ylsulfanyl)-1,4,5-trimethyl-4H-[1,2,4]triazol-1-ium; 
• 88305-18-4 Toluene-4-sulfonate3-(3,4-dihydroxy-naphthalen-1-ylsulfanyl)-1,4,5-trimethyl-4H-[1,2,4]triazol-1-ium; 
• 88305-37-7 Toluene-4-sulfonate3-(2,5-dihydroxy-phenylsulfanyl)-1,4,5-trimethyl-4H-[1,2,4]triazol-1-ium; 
• 94324-36-4 Toluene-4-sulfonate3-(1,4-dihydroxy-naphthalen-2-ylsulfanyl)-1,4,5-trimethyl-4H-[1,2,4]triazol-1-ium; 
• 88305-40-2 Toluene-4-sulfonate3-(4,5-dihydroxy-2-methyl-phenylsulfanyl)-1,4,5-trimethyl-4H-[1,2,4]triazol-1-ium; 
• 88305-38-8 Trifluoro-acetate3-(2,5-dihydroxy-phenylsulfanyl)-1,4,5-trimethyl-4H-[1,2,4]triazol-1-ium; 
• 88305-36-6 C₁₁H₁₄N₃O₂S⁽¹⁺⁾*BF₄^(1-) 
• 88305-50-4 C₁₆H₂₂N₆O₂S₂⁽²⁺⁾*2BF₄^(1-) 

Relevant academic research and scientific papers

A Study of the Behaviour of 2,4-Substituted Thiosemicarbazides toward Orthoesters: Formation of Mesoionic Compounds

The reactions beetwen 2,4-disubstituted thiosemicarbazides and orthoesters in refluxing xylene led to the formation of the 1,2,4-triazoline-5-thione ring and to the 1,2,4-triazolium-5-thiolate ring. The formation of the mesoionic componds is due to rearrangement of the easily available 2,4-disubstituted thiosemicarbazides to 1,4-disubstituted thiosemicarbazides under the reaction conditions adopted. This method can be usefully used for the synthesis of mesoionic compounds, especially in the case of the 2-methyl-4-phenylthiosemicarbazide.