173853-63-9

Basic information

• Product Name: N-(1-ethyl-1H-pyrrol-2-yl)-o-hydroxymethylbenzamide
• Synonyms: N-(1-ethyl-1H-pyrrol-2-yl)-o-hydroxymethylbenzamide
• CAS NO: 173853-63-9
• Molecular Weight: 244.293
• Mol File: 173853-63-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(1-ethyl-1H-pyrrol-2-yl)-o-hydroxymethylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-ethyl-1H-pyrrol-2-yl)-o-hydroxymethylbenzamide(173853-63-9)
• EPA Substance Registry System: N-(1-ethyl-1H-pyrrol-2-yl)-o-hydroxymethylbenzamide(173853-63-9)

Safety Data

• Hazardous Substances Data: 173853-63-9(Hazardous Substances Data)

Upstream product

• 617-92-5 1-ethyl-1H-pyrrole 
• 3481-09-2 N-chlorophthalimide 
• 173853-59-3 N-(1-ethyl-1H-pyrrol-2-yl)phthalimide 

Downstream Products

• 87-41-2 2-benzofuran-1(3H)-one 
• 173853-68-4 2-amino-1-ethylpyrrole 

Relevant articles and documents

2-Aminopyrrole and simple 1-substituted 2-aminopyrroles: Preparation and ab initio study on the effect of solvent on the amino-imino tautomeric equilibrium

This work describes the preparation and NMR characterization of 2-aminopyrrole and simple 1-substituted-2-aminopyrroles without further substitution on the ring. The question of the effect of solvent on tautomerism in 2-aminopyrroles has been studied by using ab initio quantum mechanical methods. Theoretical calculations indicated that 2-aminopyrrole is the most stable form in chloroform and in water. Experimentally this is what was observed. Calculations indicated that in the case of the 1-methyl-2-aminopyrrole both amino and imino tautomers should be observable in water.

First synthesis of 2-aminopyrrole and simple 1-substituted-2-aminopyrroles. Observation of fast proton exchange at C-5

N-(1-substituent-1H-pyrrol-2-yl)phthalimides can be used to prepare the previously unknown 2-aminopyrrole and 1-substituted-2-aminopyrroles which undergo fast proton exchange at C-5 in acetic acid at 25°C.