173928-86-4

Basic information

• Product Name: Z(OMe)-Ser-Arg(NO₂)-OBzl
• CAS NO: 173928-86-4
• Molecular Weight: 560.564
• Mol File: 173928-86-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Z(OMe)-Ser-Arg(NO₂)-OBzl(CAS DataBase Reference)
• NIST Chemistry Reference: Z(OMe)-Ser-Arg(NO₂)-OBzl(173928-86-4)
• EPA Substance Registry System: Z(OMe)-Ser-Arg(NO₂)-OBzl(173928-86-4)

Safety Data

• Hazardous Substances Data: 173928-86-4(Hazardous Substances Data)

Upstream product

• 20890-93-1 N-<<(p-methoxybenzyl)oxy>carbonyl>-L-serine 

Downstream Products

• 173928-89-7 Boc-Tyr(Bzl)-Ile-Gly-Ser-Arg(NO₂)-OBzl 

Relevant articles and documents

Amino acids and peptides. XXVI. Laminin-related peptide poly(ethylene glycol) hybrids and their inhibitory effect on experimental metastasis

Laminin-related peptide poly(ethylene glycol) hybrid, Tyr-Ile-Gly-Ser- Arg-aminopoly(ethylene glycol) was prepared by the solution method and carboxylated poly(ethylene glycol)-Tyr-Ile-Gly-Ser-Arg was prepared by the solid phase method. Their inhibitory effects on experimental tumor metastasis were examined in mice. The inhibitory effect of Tyr-Ile-Gly-Ser-Arg was significantly potentiated by hybrid formation with poly(ethylene glycol) either at amino- or carboxyl terminals of the peptide. Of the hybrids, Tyr- Ile-Gly-Ser-Arg-amino(polyethylene glycol) 6000 hybrid exhibited about 10 times more potent anti-metastatic effect than the peptide itself. The inhibitory effect of a mixture of the carboxylated poly(ethylene glycol) hybrid and Arg-Gly-Asp-aminopoly(ethylene glycol) hybrid also exhibited an inhibitory effect.