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173934-26-4

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173934-26-4 Usage

General Description

(R)-homocitric acid lactone is a chemical compound that belongs to the family of carboxylic acids and derivatives. It is a lactone derivative of (R)-homocitric acid, which is an intermediate in the metabolism of lysine and tryptophan. (R)-HOMOCITRIC ACID LACTONE has been shown to have potential biological activities, including as an inhibitor of the enzymes involved in the biosynthesis of lysine and tryptophan. It has also been studied for its potential use in the treatment of certain metabolic disorders. Additionally, (R)-homocitric acid lactone has been investigated for its role in the biosynthesis of certain natural products, making it of interest to researchers in the fields of biochemistry and organic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 173934-26-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,3,9,3 and 4 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 173934-26:
(8*1)+(7*7)+(6*3)+(5*9)+(4*3)+(3*4)+(2*2)+(1*6)=154
154 % 10 = 4
So 173934-26-4 is a valid CAS Registry Number.

173934-26-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R)-2-(carboxymethyl)-5-oxooxolane-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:173934-26-4 SDS

173934-26-4Downstream Products

173934-26-4Relevant articles and documents

Asymmetric Synthesis of Homocitric Acid Lactone

Nickerson, Leslie A.,Huynh, Valerie,Balmond, Edward I.,Cramer, Stephen P.,Shaw, Jared T.

, p. 11404 - 11408 (2016/11/28)

A short, diastereoselective synthesis of homocitric acid lactone is described. The key step is a bioinspired aldol addition to set the stereogenic center in an intermediate that requires only modest oxidation state manipulation to complete the synthesis. This approach enables rapid generation of isotopomers in which carbon and hydrogen can be replaced by heavier nuclei at nearly every position.

An improved synthesis of trisodium (U)-homocitrate from citric acid

Prokop,Milewska

experimental part, p. 1317 - 1322 (2010/07/05)

A method of synthesis of trisodium (R)-homocitrate starting from citric acid is reported. The procedure affords the final product of high optical purity with satisfactory yield.

A facile method for synthesis of (R)-(-)- and (S)-(+)-homocitric acid lactones and related α-hydroxy dicarboxylic acids from D- or L-malic acid

Xu, Peng-Fei,Matsumoto, Tsuyoshi,Ohki, Yasuhiro,Tatsumi, Kazuyuki

, p. 3815 - 3818 (2007/10/03)

We report here a simple and convenient route for the stereoselective synthesis of (R)-(-)- and (S)-(+)-homocitric acid lactones, which play very important roles in biochemistry. The method involves only three steps, starting from the readily available met

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