173974-97-5Relevant academic research and scientific papers
Reversal of stereoselectivity in the Evans aldol reaction of α,α-difluoro and α,α,α-trifluoro carbonyl compounds
Iseki, Katsuhiko,Oishi, Satoshi,Kobayashi, Yoshiro
, p. 71 - 84 (2007/10/02)
The Evans aldol reaction of hexafluoroacetone and trifluoroacetaldehyde causes complete reversal of diastereofacial selectivity. The boron enolate derived from N-acyloxazolidinone 2 reacts with trifluoroacetaldehyde to give anti and "non-Evans" syn aldols
Diastereo-face selectivity in the aldol reaction of boryl enolate derived from Oppolzer's sultam
Iseki, Katsuhiko,Oishi, Satoshi,Kobayashi, Yoshiro
, p. 2003 - 2008 (2007/10/03)
In the Oppolzer aldol reaction, aldehyde reacts exclusively on the Si face (C(α)-Si attack) of the double bond of the boryl enolate 2 derived from (1S,2R)-N-propionylbornane-10,2-sultam (1), providing only 3a stereoselectively. Hexafluoroacetone (4) cause
Reversal of Stereoselectivity in the Aldol Reaction of Boron Enolate Derived from Oppolzer's Sultam with α,α-Difluoro and α,α,α-Trifluoro Carbonyl Compounds
Iseki, Katsuhiko,Oishi, Satoshi,Kobayashi, Yoshiro
, p. 1135 - 1138 (2007/10/02)
Hexafluoroacetone causes the complete reversal of stereochemistry in the aldol reaction of boron enolate derived from Oppolzer's sultam in the absence of Lewis acids such as TiCl4.Trifluoroacetaldehyde and 2,2-difluoro-5-phenyl-1-pentanal cause partial re
Reversal of stereoselectivity in the Evans aldol reaction of α,α-difluoro and α,α,α-trifluoro carbonyl compounds
Iseki, Katsuhiko,Oishi, Satoshi,Taguchi, Takeo,Kobayashi, Yoshiro
, p. 8147 - 8150 (2007/10/02)
The Evans aldol reaction of hexafluoroacetone and trifluoroacetaldehyde causes reversal of stereoselectivity. The boron enolate derived from oxazolidinone 1 reacts with trifluoroacetaldehyde to give anti and "non-Evans" syn aldols with stereoselectivities
