174137-97-4Relevant articles and documents
A CoII complex for19F MRI-based detection of reactive oxygen species
Yu, Meng,Xie, Da,Phan, Khanh P.,Enriquez, José S.,Luci, Jeffrey J.,Que, Emily L.
supporting information, p. 13885 - 13888 (2016/12/06)
A fluorinated, air-stable cobalt(ii) complex serves as a turn-on19F magnetic resonance imaging (MRI) tracer for reactive oxygen species including H2O2. Upon oxidation with H2O2, the complex converts from paramagnetic high spin CoII to diamagnetic low spin CoIII resulting in a chemical shift change and enhancement in19F NMR signal. Further, the oxidation can be reversed in the presence of reductant Na2S2O4. The turn-on response is demonstrated by19F MRI, characterized by a ~2-3 fold enhancement in signal.
Gd3+-based magnetic resonance imaging contrast agent responsive to Zn2+
Regueiro-Figueroa, Martín,Gündüz, Serhat,Patinec, Véronique,Logothetis, Nikos K.,Esteban-Gómez, David,Tripier, Rapha?l,Angelovski, Goran,Platas-Iglesias, Carlos
, p. 10342 - 10350 (2015/11/16)
We report the heteroditopic ligand H5L, which contains a DO3A unit for Gd3+ complexation connected to an NO2A moiety through a N-propylacetamide linker. The synthesis of the ligand followed a convergent route that involved the prepar
Efficient synthesis and evaluation of bimodal ligand NETA
Chong, Hyun-Soon,Song, Hyun A.,Birch, Noah,Le, Thien,Lim, Sooyoun,Ma, Xiang
supporting information; scheme or table, p. 3436 - 3439 (2009/04/11)
The efficient and short synthetic route to the structurally novel bimodal ligand NETA for antibody-targeted radiation therapy (radioimmunotherapy, RIT) of cancer was developed. The structure of NETA was determined by X-ray crystallography. The arsenazo-ba