174139-65-2

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 3-(2-pyridinyl)-1H-pyrazole-5-carboxylate serves as a crucial building block in the synthesis of a range of biologically active compounds. Its role in creating potential anticancer and antiviral agents highlights its importance in developing new therapeutics.
Used in Pesticide and Herbicide Development:
Ethyl 3-(2-pyridinyl)-1H-pyrazole-5-carboxylate has been investigated for its potential use in agriculture as a pesticide and herbicide, indicating its broad-spectrum applicability beyond healthcare and into crop protection.
Used in Materials Science:
Ethyl 3-(2-pyridinyl)-1H-pyrazole-5-carboxylate has been studied for its application in materials science, particularly for its fluorescent properties that allow it to act as a probe for detecting metal ions. This capability can be instrumental in various analytical and environmental monitoring applications.

InChI:InChI=1/C11H11N3O2/c1-2-16-11(15)10-7-9(13-14-10)8-5-3-4-6-12-8/h3-7H,2H2,1H3,(H,13,14)

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 1945-84-2 2-ethynylpyridine 
• 1122-62-9 2-acetylpyridine 
• 92288-93-2 ethyl 2,4-dioxo-4-(pyridin-2-yl)butanoate 

Downstream Products

• 1323076-28-3 ethyl 1-[2-(4-chlorophenyl)-2-oxoethyl]-5-(pyridin-2-yl)-1H-pyrazole-3-carboxylate 
• 1323076-26-1 ethyl 1-[2-(4-chlorophenyl)-2-oxoethyl]-3-(pyridin-2-yl)-1H-pyrazole-5-carboxylate 
• 1323076-30-7 10a-(4-chlorophenyl)-7-(pyridin-2-yl)-2,3,10,10a-tetrahydro-1H,5H-imidazo[1,2-a]pyrazolo[1,5-d]pyrazin-5-one 
• 1323074-53-8 10a-(4-chlorophenyl)-1-[(3-methyl-1,2-oxazol-4-yl)carbonyl]-7-(pyridin-2-yl)-2,3,10,10a-tetrahydro-1H,5H-imidazo[1,2-a]pyrazolo[1,5-d]pyrazin-5-one 
• 1338351-71-5 ethyl 1-[2-(4-fluorophenyl)ethyl]-3-(pyridin-2-yl)-1H-pyrazole-5-carboxylate 

Relevant academic research and scientific papers

DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis

Visceral leishmaniasis (VL) is a parasitic disease endemic across multiple regions of the world and is fatal if untreated. Current therapies are unsuitable, and there is an urgent need for safe, short-course, and low-cost oral treatments to combat this ne

MULTISUBSTITUTED AROMATIC COMPOUNDS AS INHIBITORS OF THROMBIN

There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing a disease or disorder, which disease or disorder is amenable to treatment or prevention by the inhibition of thrombin.

Condensed pyrazole derivative

The present invention provides cyclic aminomethylpyrimidine derivatives and pharmaceutically acceptable salts thereof which show high selectivity for dopamine D4 receptors and are useful for treating diseases such as attention deficit hyperacti

Synthesis, structure–activity relationships and biological evaluation of 4,5,6,7-tetrahydropyrazolopyrazines as metabotropic glutamate receptor 5 negative allosteric modulators

The design, synthesis and SAR studies of novel 4,5,6,7-tetrahydropyrazolopyrazines as metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulators (NAMs) are presented in this letter. Starting from a HTS hit compound (1, IC50?=?477

PYRAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful

A facile synthesis of pyrazoles with multi-point structural diversity by 1,3-dipolar cycloaddition

We describe the synthesis of diverse pyrazoles by 1,3-dipolar cycloaddition of ethyl diazoacetate with various acetylenes in refluxing toluene. The product pyrazoles are useful starting points for preparing a diverse collection of trisubstituted pyrazole

1,3-Dipolar cycloaddition of diazoacetate compounds to terminal alkynes promoted by Zn(OTf)2: an efficient way to the preparation of pyrazoles

A series of pyrazoles were prepared in good yields via 1,3-dipolar cycloaddition of diazoacetate compounds to terminal alkynes promoted by Zn(OTf)2 under mild conditions. It was supposed that the reaction was through the intermediate of Zn alky