17415-32-6

Basic information

• Product Name: 3-amino-2-methyl-4-phenylisoxazol-5(2H)-one
• CAS NO: 17415-32-6
• Molecular Weight: 190.202
• Mol File: 17415-32-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-amino-2-methyl-4-phenylisoxazol-5(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-2-methyl-4-phenylisoxazol-5(2H)-one(17415-32-6)
• EPA Substance Registry System: 3-amino-2-methyl-4-phenylisoxazol-5(2H)-one(17415-32-6)

Safety Data

• Hazardous Substances Data: 17415-32-6(Hazardous Substances Data)

Upstream product

• 74-88-4 methyl iodide 
• 17415-26-8 3-Amino-4-phenylisoxazol-5(2H)-one 
• 4229-44-1 N-methylhydroxyamine hydrochloride 
• 4553-07-5 ethyl phenylcyanoacetate 

Downstream Products

• 223802-39-9 2-methoxy-2-phenyl-N-methyl-N-hydroxyacetamidine 
• 88070-48-8 N-methylbenzamide 
• 7476-63-3 (+/-)-2-methoxy-2-phenylacetamide 

Relevant articles and documents

The Chemistry of 5-Oxodihydroisoxazoles. Part 23. Photochemical and Thermal Reactions of Isoxazol-5(2H)-ones Substituted at C-3 or C-4 with Nitrogen, Oxygen or Sulfur

The photolysis of 2,3-dimethyl-4-phenoxy- and 4-thiophenoxyisoxazol-5(2H)-one in methanol has been re-examined, but no new products were isolated. Flash vacuum pyrolysis of the former gave a novel product, phenyl N-methylpropenimidate, from rearrangement of the intermediate carbene. Irradiation of the 3-hydroxy-2-phenyl-4-carboxylate gave two products which arise from the 3-hydroxy and 5-hydroxy tautomers. By contrast, the 3-hydroxy-4-acetyl isoxazolone reacted exclusively as one tautomer giving the expected loss of CO2 to form the carbene which was captured by methanol on photolysis, or underwent methyl migration and cyclisation to 3-methylazetidine-1,3-dione on pyrolysis. 3-Amino and 3-phenylamino substituted isoxazolones also gave photolysis and pyrolysis products characteristic of discrete tautomers.