17416-64-7

Basic information

• Product Name: 5,12b-dihydroisoindolo[1,2-a]isoquinolin-8(6H)-one
• Synonyms: 5,12b-Dihydroisoindolo[1,2-a]isoquinolin-8(6H)-one; isoindolo[1,2-a]isoquinolin-8(6H)-one, 5,12b-dihydro-
• CAS NO: 17416-64-7
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 235.2805
• Mol File: 17416-64-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 406.9°C at 760 mmHg
• Flash Point: 194.7°C
• Density: 1.29g/cm³
• Vapor Pressure: 7.86E-07mmHg at 25°C
• Refractive Index: 1.695
• CAS DataBase Reference: 5,12b-dihydroisoindolo[1,2-a]isoquinolin-8(6H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,12b-dihydroisoindolo[1,2-a]isoquinolin-8(6H)-one(17416-64-7)
• EPA Substance Registry System: 5,12b-dihydroisoindolo[1,2-a]isoquinolin-8(6H)-one(17416-64-7)

Safety Data

• Hazardous Substances Data: 17416-64-7(Hazardous Substances Data)

Upstream product

• 52721-69-4 [2-(2-fluorophenyl)ethyl]amine 

Downstream Products

• 1417504-10-9 3,4-dihydro-1-phenylisoquinoline-2'-carboxylic acid hydrochloride 
• 1417504-09-6 3,4-dihydro-1-(2'-methoxycarbonylphenyl)isoquinoline hydrochloride 

Relevant articles and documents

A new approach to isoindoloisoquinolinones. A simple synthesis of nuevamine

A convenient and versatile short step synthesis of isoindoloisoquinolinones, illustrated by the total synthesis of the alkaloid nuevamine 1a, is described. The tetracyclic lactam compounds were obtained by a tactical combination of the Parham procedure for the elaboration of the isoindolinone template and an aryne-mediated cyclization giving rise to the nitrogen containing six-membered heteroring unit.