174182-34-4

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 174291-96-4 (1R,2R)-(-)-N-p-tosyl-1,2-cyclohexanediamine 
• 20439-47-8 (1R,2R)-1,2-diaminocyclohexane 

Downstream Products

• 174182-35-5 [((1R,2R)-2-tert-Butoxycarbonylamino-cyclohexyl)-(toluene-4-sulfonyl)-amino]-acetic acid 
• 190600-51-2 [((1R,2R)-2-{2-[((1R,2R)-2-tert-Butoxycarbonylamino-cyclohexyl)-(toluene-4-sulfonyl)-amino]-acetylamino}-cyclohexyl)-(toluene-4-sulfonyl)-amino]-acetic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of conformationally tailored pentaazacyclopentadeeanes. Preorganizing peptide cyclizations.

A general method for the preparation of rigidified pentaazamacrocycles using trans-(1R,2R)-diaminocyclohexane as the conformational controller element. High macrocyclization yields have been obtained by strategic placement of the diamino-cyclohexane group within the pseudopeptide backbone.