17424-49-6

Usage

Uses

Used in Perfumery and Fragrance Industry:
2,4-Heptanedione, 7-phenylis used as a fragrance ingredient for its pleasant aroma, contributing to the creation of various perfumes and other fragrance products.
Used in Pharmaceutical Industry:
2,4-Heptanedione, 7-phenylis used as a building block in the synthesis of organic compounds and as a reagent in chemical reactions, playing a crucial role in the production of certain pharmaceuticals.
Used in Food Industry:
2,4-Heptanedione, 7-phenylis used as a flavoring agent, enhancing the taste and aroma of various food products.

Upstream product

• 637-59-2 1-Bromo-3-phenylpropane 
• 123-54-6 acetylacetone 
• 1450727-09-9 C₁₆H₂₀O₄ 
• 155125-29-4 2-Methyl-2-((E)-2-nitro-5-phenyl-pent-2-enyl)-[1,3]dioxolane 
• 155125-37-4 1-(2-Methyl-[1,3]dioxolan-2-yl)-5-phenyl-pentan-2-one 

Downstream Products

• 1821-12-1 4-Phenylbutyric acid 
• 1333415-24-9 2-(3-phenylpropyl)-4-(phenylsulfonylmethyl)furan 
• 128496-98-0 2-Methyl-4-<(phenylsulfonyl)methyl>furan 
• 1431791-84-2 1-(2-hydroxy-5-phenylcyclopent-1-en-1-yl)ethanone 
• 1431791-07-9 3-diazo-7-phenylheptane-2,4-dione 

Relevant academic research and scientific papers

Microwave-assisted aqueous Krapcho decarboxylation

The Krapcho decarboxylation of alkyl malonate derivatives has been adapted to aqueous microwave conditions. Various salt additives were examined, and both the cation and the anion impacted the facility of the reaction. A strong correlation was found between the pKa of the anion and the reaction rate, suggesting a straightforward base-catalyzed hydrolysis. Lithium sulfate gave the best results, obviating the need for DMSO co-solvent. Georg Thieme Verlag Stuttgart · New York.

Mild conversion of β-diketones and β-ketoesters to carboxylic acids

A mild protocol for the conversion of β-ketoesters and β-diketones to carboxylic acids with use of CAN in CH3CN is described. The method is compatible with a number of functional groups, and can generate carboxylic acids under neutral conditions at room temperature. The reaction is fast and general, providing an alternative method to the commonly used malonic ester acid preparation. Initial mechanistic studies show that initial oxidation of the enol form of the β-dicarbonyl initiates the reaction. The presence of nitrate as an oxidant ligand or as an additive is critical for success of the reaction.

A new, simple, and general synthesis of 1,3-, 1,4- and 1,5-diketones from functionalized nitroalkanes

Herein is reported the utilization of protected nitro ketones, in the synthesis of 1,3-, 1,4-, and 1,5-diketones, by their condensation with aldehydes then conversion of the obtained conjugated nitroalkenes into monoprotected carbonyl derivatives which, by removal of the protecting group, gives diketones.