17428-97-6Relevant academic research and scientific papers
Iron-Catalyzed ?±,?-Dehydrogenation of Carbonyl Compounds
Zhang, Xiao-Wei,Jiang, Guo-Qing,Lei, Shu-Hui,Shan, Xiang-Huan,Qu, Jian-Ping,Kang, Yan-Biao
supporting information, p. 1611 - 1615 (2021/03/03)
An iron-catalyzed α,β-dehydrogenation of carbonyl compounds was developed. A broad spectrum of carbonyls or analogues, such as aldehyde, ketone, lactone, lactam, amine, and alcohol, could be converted to their α,β-unsaturated counterparts in a simple one-step reaction with high yields.
Efficient and convenient heterogeneous palladium-catalyzed regioselective deuteration at the benzylic position
Kurita, Takanori,Hattori, Kazuyuki,Seki, Saori,Mizumoto, Takuto,Aoki, Fumiyo,Yamada, Yuki,Ikawa, Kanoko,Maegawa, Tomohiro,Monguchi, Yasunari,Sajiki, Hironao
, p. 664 - 673 (2008/12/21)
The Pd/C-catalyzed efficient and regioselective hydrogen-deuterium (H-D) exchange reaction on the benzylic site proceeded in D2O in the presence of a small amount of H2 gas. The use of the Pd/C-ethylenediamine complex [Pd/C(en)] as a catalyst instead of Pd/C led to the efficient deuterium incorporation into the benzylic site of Obenzyl protective groups without hydrogenolysis. These H-D exchange reactions provide a post synthetic and D2-gas-free deuterium-labeling method on a wide variety of benzylic sites using D2O as the deuterium source and heterogeneous Pd/C or Pd/C(en) as a reusable heterogeneous palladium catalyst under mild and neutral conditions.
METHOD OF DEUTERIZING BENZYL-POSITION IN -O-BENZYL GROUP
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Page/Page column 8, (2008/12/09)
(PROBLEM) To provide a method for efficiently and industrially deuterating the benzyl position of a -O-benzyl group formed by introducing a benzyl group, a benzyloxymethyl group and the like as a protecting group. (SOLUTION) The deuteration method for the benzyl position of a -O-benzyl group of a compound having the -O-benzyl group which may have a substituent, comprising reacting the compound with a heavy hydrogen source in the coexistence of a palladium/carbon-ethylenediamine complex and hydrogen.
Pd/C-H2-catalysed deuterium exchange reaction of the benzylic site in D2O
Sajiki, Hironao,Hattori, Kazuyuki,Aoki, Fumiyo,Yasunaga, Kanoko,Hirota, Kosaku
, p. 1149 - 1151 (2007/10/03)
Pd/C is found to catalyse efficient and chemoselective exchange of deuterium derived from D2O with hydrogens on a benzylic carbon in the presence of a catalytic amount of hydrogen at room temperature.
