174282-91-8

Basic information

• Product Name: (2R,3S)-1-tert-butyldimethylsilyloxy-3-tert-butoxycarbonylamino-2-p-nitrophenylcarbonyloxybutane
• CAS NO: 174282-91-8
• Molecular Weight: 468.623
• Mol File: 174282-91-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3S)-1-tert-butyldimethylsilyloxy-3-tert-butoxycarbonylamino-2-p-nitrophenylcarbonyloxybutane(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S)-1-tert-butyldimethylsilyloxy-3-tert-butoxycarbonylamino-2-p-nitrophenylcarbonyloxybutane(174282-91-8)
• EPA Substance Registry System: (2R,3S)-1-tert-butyldimethylsilyloxy-3-tert-butoxycarbonylamino-2-p-nitrophenylcarbonyloxybutane(174282-91-8)

Safety Data

• Hazardous Substances Data: 174282-91-8(Hazardous Substances Data)

Upstream product

• 154079-54-6 (2S,3S)-3-tert-butoxycarbonylamino-1,2-butanediol 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 174282-97-4 (2R,3S)-3-tert-butoxycarbonylamino-2-hydroxybutanoic acid 
• 174282-92-9 (2R,3S)-3-tert-butoxycarbonylamino-2-p-nitrophenylcarbonyloxy-1-butanol 

Relevant articles and documents

An enantioselective, stereodivergent approach to anti- and syn-α-hydroxy-β-amino acids from anti-3-amino-1,2-diols. Synthesis of the ready for coupling Taxotere side chain

Both anti- and syn-α-hydroxy-β-amino acids are efficiently synthesised in protected form and high enantiomeric purity from readily available anti-N-Boc-1-tert-butyldimethylsilyl-3-amino-1,2-diols. The preparation of the anti series is straightforward, and