17429-94-6

Basic information

• Product Name: 2-Acetylamino-3-O-methyl-2-deoxy-α-D-galactopyranose 1,4,6-triacetate
• Synonyms: 2-Acetylamino-3-O-methyl-2-deoxy-α-D-galactopyranose 1,4,6-triacetate
• CAS NO: 17429-94-6
• Molecular Formula: C15H23NO9
• Molecular Weight: 361.34442
• Mol File: 17429-94-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Acetylamino-3-O-methyl-2-deoxy-α-D-galactopyranose 1,4,6-triacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Acetylamino-3-O-methyl-2-deoxy-α-D-galactopyranose 1,4,6-triacetate(17429-94-6)
• EPA Substance Registry System: 2-Acetylamino-3-O-methyl-2-deoxy-α-D-galactopyranose 1,4,6-triacetate(17429-94-6)

Safety Data

• Hazardous Substances Data: 17429-94-6(Hazardous Substances Data)

Upstream product

• 117177-19-2 2-methyl-(1,2-dideoxy-5,6-O-isopropylidene-α-D-glucofurano)-<2,1-d>-2-oxazoline 
• 7512-17-6 N-Acetyl-D-glucosamine 
• 108-24-7 acetic anhydride 

Relevant articles and documents

Synthesis of N -acetyl glucosamine analogs as inhibitors for hyaluronan biosynthesis

Elevated hyaluronan expression is a hallmark of many types of cancer. Therefore, inhibition of hyaluronan biosynthesis can potentially slow the growth of tumor cells. Herein, we explore a chain termination strategy to reduce hyaluronan synthesis by tumor cells. Several analogs of glucosamine were prepared, which contained modifications at the C-3 positions. These analogs can possibly cap the nonreducing end of a growing hyaluronan chain, thus lowering the amount of hyaluronan synthesized. Upon incubation with pancreatic cancer cells, a fluorine-containing glucosamine analog was found to exhibit significant inhibitory activities of hyaluronan synthesis. Furthermore, it drastically reduced the proliferation of cancer cells. Supplemental materials are available for this article. Go to the publisher's online edition of Journal of Carbohydrate Chemistry to view the supplemental file.