1743-87-9

Usage

Uses

Used in Chemical Industry:
5,6,7,8-Tetrafluorobenzo-1,4-dioxane is used as a solvent in various chemical processes due to its high stability and low reactivity. Its ability to dissolve a wide range of substances makes it a valuable component in the production of various chemicals.
Used in Pharmaceutical Industry:
5,6,7,8-Tetrafluorobenzo-1,4-dioxane serves as an intermediate in the synthesis of certain pharmaceutical compounds. Its unique properties allow for the development of new drugs with improved efficacy and reduced side effects.
Used in Agrochemical Industry:
In the agrochemical sector, 5,6,7,8-tetrafluorobenzo-1,4-dioxane is utilized as a starting material for the production of various agrochemicals, including pesticides and herbicides. Its stability and resistance to degradation contribute to the effectiveness and longevity of these products.
Used in Research and Development:
5,6,7,8-Tetrafluorobenzo-1,4-dioxane is employed in research and development for the exploration of new chemical reactions and the synthesis of novel compounds. Its unique properties make it an attractive candidate for studying the effects of fluorination on chemical reactivity and stability.

InChI:InChI=1/C8H4F4O2/c9-3-4(10)6(12)8-7(5(3)11)13-1-2-14-8/h1-2H2

Upstream product

• 2192-55-4 2-(pentafluorophenoxy)ethanol 
• 159752-87-1 Trimethyl-(2-pentafluorophenyloxy-ethoxy)-silane 
• 107-21-1 ethylene glycol 

Relevant academic research and scientific papers

A novel perfluoromonomer: Perfluoro-2,3-dihydro-1,4-benzodioxin

A novel perfluoromonomer, perfluoro-2,3-dihydro-1,4-benzodioxin (FDB), was synthesized. The homopolymerization and copolymerizations of FDB were investigated. The structure and physical properties of those polymers were characterized.

Reaction of hexafluorobenzene with trimethylsilyl ethers

Hexafluorobenzene reacts readily with a variety of trimethylsilyl ethers ROSiMe3 (R = CF3CH2, FCH2CH2, H(CF2)nCH2 (n = 2, 4), CF3(CF2)6CH2, CF3(CF2)5CH2CH2, Me3SiOCH2CH2, C6F5OCH2CH2, C6H5, 4-FC6H4) to give from mono- to hexapolyfluoroalkoxy- and polyfluoroaryloxy-benzenes.The structure of C6(OCH2CF3)6 has been confirmed by single-crystal X-ray analysis.The perfluorinated ether C6F5OCF2CF3 may be synthesized from C6F5OCH2CF3 by chlorination and subsequent fluorination with SbF3/SbCl5.The chlorination of 5,6,7,8-tetrafluoro-1,4-benzodioxane is also discussed.

REACTION OF AROMATIC COMPOUNDS WITH NUCLEOPHILIC REAGENTS IN LIQUID AMMONIA. XI. REACTIONS OF HEXAFLUOROBENZENE WITH THE SODIUM SALTS OF ETHYLENE GLYCOL AND AMINO- AND MERCAPTOETHANOL

In the reaction of hexafluorobenzene with sodium ethylene glycolate in liquid ammonia at -40 to 33 deg C 1,2-di(pentafluorophenoxy)ethane and (with an excess of the reagent) 6,7,9,10,16,17,19,20-octafluoro-1,4,11,14-tetraoxaparacyclophane are formed with almost quantitative yields.The reaction of hexafluorobenzene with the sodium salt of aminoethanol under the same conditions gave β-aminoethoxypentafluorobenzene, while the action both of mercaptoethanol itself and of its sodium salt led to substitution of the two para-oriented fluorine atoms by β-hydroxyethylthio groups.