174311-38-7

Basic information

• Product Name: 1H-Indole,2,3-dihydro-1,2-dimethyl-,(2R)-(9CI)
• Synonyms: 1H-Indole,2,3-dihydro-1,2-dimethyl-,(2R)-(9CI)
• CAS NO: 174311-38-7
• Molecular Formula: C10H13N
• Molecular Weight: 0
• Product Categories: AMINETERTIARY
• Mol File: 174311-38-7.mol
• Article Data: 24

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Indole,2,3-dihydro-1,2-dimethyl-,(2R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole,2,3-dihydro-1,2-dimethyl-,(2R)-(9CI)(174311-38-7)
• EPA Substance Registry System: 1H-Indole,2,3-dihydro-1,2-dimethyl-,(2R)-(9CI)(174311-38-7)

Safety Data

• Hazardous Substances Data: 174311-38-7(Hazardous Substances Data)

Upstream product

• 62058-93-9 1,1,2-trimethyl-indolinium; iodide 
• 6872-06-6 2-methyl indoline 
• 74-88-4 methyl iodide 
• 6628-07-5 N-allyl-N-methylaniline 
• 50-00-0 formaldehyd 
• 67-68-5 dimethyl sulfoxide 
• 95-20-5 2-methyl-1H-indole 
• 64-18-6 formic acid 
• 875-79-6 1,2-dimethylindole 
• 174311-37-6 (R)-2-methylindoline allyl carbamate 
• 90563-52-3 α-methylindole 
• 124-38-9 carbon dioxide 
• 274-07-7 benzo[1,3,2]dioxaborole 
• 917377-80-1 2-methylindoline allyl carbamate 

Downstream Products

• 887690-37-1 1,2-dimethyl-indoline-5-carbaldehyde 
• 62058-93-9 1,1,2-trimethyl-indolinium; iodide 
• 87401-40-9 1,2-dimethyl-octahydro-indole 
• 87926-14-5 2-propyl-N-methyl-aniline 
• 87401-40-9 (+/-)-1,2ξ-dimethyl-(3ar,7at)-octahydro-indole 

Relevant articles and documents

Regio- and diastereoselective formation of some (η6-2-methylindoline)tricarbonylchromium(0) complex derivatives

Complexation of 2-methylindoline 1 and its derivatives 2 and 3 with Cr(CO)6 gave complexes 4-9. With the TIPS group attached to the nitrogen atom as in compound 3, the complexation was completely diastereoselective producing the endo complex 9.

Homocarbonates as substrates for the enantioselective enzymatic protection of amines

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Utilization of renewable formic acid from lignocellulosic biomass for the selective hydrogenation and/or N-methylation

Lignocellulosic biomass is one of the most abundant renewable sources in nature. Herein, we have developed the utilization of renewable formic acid from lignocellulosic biomass as a hydrogen source and a carbon source for the selective hydrogenation and further N-methylation of various quinolines and the derivatives, various indoles under mild conditions in high efficiencies. N-methylation of various anilines is also developed. Mechanistic studies indicate that the hydrogenation occurs via a transfer hydrogenation pathway.

Selective C-H Olefination of Indolines (C5) and Tetrahydroquinolines (C6) by Pd/S,O-Ligand Catalysis

Herein, we report a highly selective C-H olefination of directing-group-free indolines (C5) and tetrahydroquinolines (C6) by Pd/S,O-ligand catalysis. In the presence of the S,O-ligand, a wide range of challenging indolines, tetrahydroquinolines, and olefins was efficiently olefinated under mild reaction conditions. The synthetic potential of this methodology was demonstrated by the efficient olefination of several indoline-based natural products.