174312-93-7

Basic information

• Product Name: Ethyl 3-(2,4-dichloro-5-nitrophenyl)-3-oxopropanoate
• Synonyms: Ethyl 3-(2,4-dichloro-5-nitrophenyl)-3-oxopropanoate
• CAS NO: 174312-93-7
• Molecular Formula: C₁₁H₉Cl₂NO₅
• Molecular Weight: 306
• Mol File: 174312-93-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethyl 3-(2,4-dichloro-5-nitrophenyl)-3-oxopropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 3-(2,4-dichloro-5-nitrophenyl)-3-oxopropanoate(174312-93-7)
• EPA Substance Registry System: Ethyl 3-(2,4-dichloro-5-nitrophenyl)-3-oxopropanoate(174312-93-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 174312-93-7(Hazardous Substances Data)

Usage

General Description

Ethyl 3-(2,4-dichloro-5-nitrophenyl)-3-oxopropanoate is a chemical compound with the molecular formula C11H10Cl2NO6. It is a yellow crystalline solid that is used in the synthesis of pharmaceuticals and agrochemicals. Ethyl 3-(2,4-dichloro-5-nitrophenyl)-3-oxopropanoate is known for its antimicrobial properties and is used as a key intermediate in the production of various drugs and pesticides. It is important to handle this chemical with caution, as it is considered to be harmful if swallowed or inhaled, and can cause skin and eye irritation. Additionally, proper safety measures should be taken when handling and storing this compound to prevent any potential hazards.

Upstream product

• 6148-64-7 ethyl potassium malonate 
• 713-28-0 2,4-dichloro-5-nitro benzoyl chloride 
• 35227-78-2 diethyl (ethoxymagnesio)malonate 
• 174312-92-6 diethyl 2,4-dichloro-5-nitrobenzoylmalonate 

Downstream Products

• 148926-94-7 ethyl ester of 3-dimethylamino-2-(5-nitro-2,4-dichlorobenzoyl)acrylic acid 
• 173061-62-6 ethyl ester of 3-ethylamino-2-(5-nitro-2,4-dichlorobenzoyl)acrylic acid 
• 148926-95-8 ethyl ester of 3-cyclopropylamino-2-(5-nitro-2,4-dichlorobenzoyl)acrylic acid 
• 127625-17-6 ethyl ester of 1-cyclopropyl-6-nitro-4-oxo-7-chloro-1,4-dihydroquinoline-3-carboxylic acid 
• 109308-73-8 ethyl ester of 2-(5-nitro-2,4-dichlorobenzoyl)-3-ethoxyacrylic acid 
• 129587-22-0 2-(2-pyrrolidinylene)-3-oxo-3-(2,4-dichloro-5-nitrophenyl)propanoic acid ethyl ester 

Relevant articles and documents

Synthesis and antimycobacterial activities of novel 6-nitroquinolone-3-carboxylic acids

Various 1-(substituted)-1,4-dihydro-6-nitro-4-oxo-7-(sub-secondary amino)-quinoline-3-carboxylic acids were synthesized from 2,4-dichlorobenzoic acid by six step synthesis. The compounds were evaluated for antimycobacterial in vitro and in vivo against My

Imidazo- and triazoloquinolones as antibacterial agents. Synthesis and structure-activity relationships

4,5-Disubstituted 6-cyclopropyl-6,9-dihydro-9-oxo-1H-imidazo- (30-32) and triazolo[4,5-f]quinoline-8-carboxylic acids (33-35) were synthesized starting from 5,6-diaminoquinolones 25. The imidazoquinolones 30-32 were equal or superior to the corresponding triazoloquinolone analogues 33-35 in in vitro antibacterial activity. As for the C-5 substituents, a fluorine atom was the most favorable of the three groups, H, F, and Cl. Among the compounds prepared, 4-(cyclic amino)-5-fluoro-imidazoquinolones 31a-d showed potent and well-balanced antibacterial activity against both gram-positive and gram- negative bacteria. Structure-activity relationships for the C-4 substituents (cyclic amino groups) were also examined in detail.