174337-36-1Relevant academic research and scientific papers
Condensed heterocyclic compounds, their production and use
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, (2008/06/13)
Compounds represented by the formula: STR1 wherein ring A is benzene; Ar is aromatic group; R1, R2 and R3 each stands for H, acyl, hydrocarbon or heterocyclic, or R2 and R3, taken together, may form non-aromatic cyclic hydrocarbon; X is methylene or carbonyl; ......... is single bond or double bond; when ......... is single bond, Y is --NR4 -- (R4 is H, acyl, hydrocarbon or heterocyclic), when ......... is double bond, Y is N; n is 1-3, provided that, X is carbonyl and, at the same time, R2 and R3, taken together, form non-aromatic cyclic hydrocarbon, ......... is double bond or R4 is a heterocyclic or --Z(CH2)m --W (Z is methylene or carbonyl, W is optionally substituted amino, and m denotes 0-5), or salts thereof have an excellent GnRH receptor antagonistic action and/or an action of improving sleep disturbances.
