17435-78-8

Basic information

• Product Name: cholesterol glucuronide
• Synonyms: cholesterol glucuronide
• CAS NO: 17435-78-8
• Molecular Formula: C33H54 O7
• Molecular Weight: 562.78
• Mol File: 17435-78-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 686.3°Cat760mmHg
• Flash Point: 211.4°C
• Appearance: /
• Density: 1.19g/cm³
• Vapor Pressure: 8.4E-22mmHg at 25°C
• Refractive Index: 1.564
• CAS DataBase Reference: cholesterol glucuronide(CAS DataBase Reference)
• NIST Chemistry Reference: cholesterol glucuronide(17435-78-8)
• EPA Substance Registry System: cholesterol glucuronide(17435-78-8)

Safety Data

• Hazardous Substances Data: 17435-78-8(Hazardous Substances Data)

Usage

Description

Cholesterol glucuronide is a biomarker and a metabolite of cholesterol that plays a significant role in various physiological and pathological processes. It is involved in the regulation of cholesterol homeostasis and has been linked to several diseases, including cancer, osteoporosis, neurodegenerative disorders, cognitive and psychiatric disorders, cardiovascular diseases, and obesity.

Uses

Used in Medical Research:
Cholesterol glucuronide is used as a biomarker for comprehensive profiling of the steroid metabolome in relation to various diseases. Its analysis helps in understanding the underlying mechanisms and pathophysiology of these conditions, which can lead to the development of targeted therapies and personalized treatment strategies.
Used in Cancer Research:
Cholesterol glucuronide is used as a diagnostic and prognostic marker in cancer research. Its elevated levels have been associated with certain types of cancer, making it a potential indicator for early detection, monitoring disease progression, and evaluating treatment response.
Used in Osteoporosis Research:
In the context of osteoporosis, cholesterol glucuronide is used as a biomarker to study the relationship between cholesterol metabolism and bone health. This can help in understanding the role of cholesterol in bone remodeling and the development of osteoporotic conditions.
Used in Neurodegenerative Disease Research:
Cholesterol glucuronide is used as a biomarker in the study of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Its involvement in cholesterol metabolism and its association with these diseases can provide insights into the molecular mechanisms underlying their pathogenesis.
Used in Cognitive and Psychiatric Disorder Research:
Cholesterol glucuronide is used as a biomarker in the research of cognitive and psychiatric disorders, including depression and schizophrenia. Its role in cholesterol metabolism and its association with these conditions can help in understanding the complex interplay between cholesterol and brain function.
Used in Cardiovascular Disease Research:
In cardiovascular disease research, cholesterol glucuronide is used as a biomarker to study the relationship between cholesterol metabolism and heart disease. This can aid in the development of novel therapeutic approaches targeting cholesterol metabolism to prevent or treat cardiovascular diseases.
Used in Obesity Research:
Cholesterol glucuronide is used as a biomarker in obesity research to investigate the link between cholesterol metabolism and body weight regulation. Understanding this relationship can contribute to the development of strategies for obesity prevention and management.

InChI:InChI=1/C33H54O7/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(13-15-32(20,4)25(22)14-16-33(23,24)5)39-31-28(36)26(34)27(35)29(40-31)30(37)38/h9,18-19,21-29,31,34-36H,6-8,10-17H2,1-5H3,(H,37,38)/t19-,21?,22?,23?,24?,25?,26+,27+,28-,29+,31-,32+,33-/m1/s1