174356-61-7Relevant academic research and scientific papers
Rationally designed syntheses of high-mannose and complex type undecasaccharides
Nakahara, Yuko,Shibayama, Shohei,Nakahara, Yoshiaki,Ogawa, Tomoya
, p. 67 - 84 (1996)
Synthetic routes are described to a high-mannose type triantenary undecasaccharide 1 and a completely protected form 39 of the complex type biantenary undecasaccharide 2 carrying α-(2 → 3)-linked sialic acid residues. Starting from a previously reported t
Rapid access to an orthogonally protected Lewis X derivative: An important building block for synthesis of Lewis antigens
Ohmae, Masashi,Takada, Junko,Murakami, Hiroaki,Kimura, -Shunsaku
, p. 438 - 439 (2011/06/23)
A novel Lewis X derivative of 1 with an orthogonal set of protecting groups was systematically prepared. Efficient use of the protecting groups for the amino and the hydroxy groups in lactosamine enabled formation of the diol derivative at C3 and C2'. Glycosidation of 1-thio-L-fucoside donor with the diol derivative progressed preferably at the C3 hydroxy group, resulting in prior production of 1. Compound 1 is a key building block toward easy assemblies of Lewis X-related carbohydrate epitopes.
