1744-46-3

Basic information

• Product Name: Pyridine, 2-(pentafluoroethyl)- (7CI,8CI,9CI)
• Synonyms: Pyridine, 2-(pentafluoroethyl)- (7CI,8CI,9CI)
• CAS NO: 1744-46-3
• Molecular Formula: C₇H₄F₅N
• Molecular Weight: 197.105376
• Product Categories: PYRIDINE
• Mol File: 1744-46-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyridine, 2-(pentafluoroethyl)- (7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2-(pentafluoroethyl)- (7CI,8CI,9CI)(1744-46-3)
• EPA Substance Registry System: Pyridine, 2-(pentafluoroethyl)- (7CI,8CI,9CI)(1744-46-3)

Safety Data

• Hazardous Substances Data: 1744-46-3(Hazardous Substances Data)

Upstream product

• 109-09-1 2-chloropyridine 
• 75-61-6 dibromodifluoromethane 
• 5029-67-4 2-iodopyridine 
• 110-86-1 pyridine 
• 2314-97-8 iodotrifluoromethane 

Relevant articles and documents

The solid complex Zn(CF3)Br·2DMF as an alternative reagent for the preparation of both, trifluoromethyl and pentafluoroethyl copper, CuCF3 and CuC2F5

Trifluoromethylcopper and pentafluoroethylcopper are prepared conveniently via the reaction of the solid complex Zn(CF3)Br·2DMF with copper(I) bromide in N,N-dimethylformamide. The reactions of both copper species with 2,4-dinitrochlorobenzene,

Studies on Organic Fluorine Compounds. Part 27. Abnormal Reactions in the Trifluoromethylation of Aromatic Compounds with Trifluoromethyl Iodide and Copper Powder

Reaction of 3-bromobenzofuran with trifluoromethyl iodide and copper powder in pyridine gave 2-(trifluoromethyl)-, 2- and 3-(pentafluoroethyl)-, and 2,3-bis(trifluoromethyl)-benzofuran, as well as the expected product, 3-(trifluoromethyl)benzofuran.Bromoanisole also gave (trifluoromethyl)anisole and (pentafluoroethyl)anisole, but introduction of the perfluoroalkyl group occurred at the position originally occupied by the bromine.Formation of pentafluoroethyl compounds is explained by decomposition of trifluoromethylcopper to cuprous fluoride and difluorocarbene, which can then react with a further molecule of trifluoromethylcopper to form pentafluoroethylcopper.This then reacts with aryl halide to give pentafluoroethyl compounds.Perfluoroalkylcopper is thermally cleaved to perfluoroalkyl radical, which then reacts with pyridine to give perfluoroalkylpyridines.This mechanism must be involved in the formation of 2,3-bis(trifluoromethyl)benzofuran.Introduction of a perfluoroalkyl group to the position originally unoccupied with halogen might be due to the rather localized double bond in benzofuran.