174420-19-0

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 188938-30-9 (2S,3S,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-3,5-dimethyl-hexane-1,2-diol 
• 174420-17-8 (2S,3R,4R)-3,5-Dimethyl-hexane-1,2,4-triol 
• 188938-28-5 (3S,4S,5R)-5-Isopropyl-4-methyl-tetrahydro-furan-2,3-diol 
• 174420-15-6 1-((3aS,5S,6S,6aS)-2,2,6-Trimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-ethanone 
• 174513-83-8 (3aS,5S,6R,6aS)-5-Isopropenyl-2,2,6-trimethyl-tetrahydro-furo[2,3-d][1,3]dioxole 
• 174693-03-9 1-((3aS,5S,6R,6aS)-2,2,6-Trimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-ethanol 
• 174513-84-9 (3aS,5R,6R,6aS)-5-Isopropyl-2,2,6-trimethyl-tetrahydro-furo[2,3-d][1,3]dioxole 
• 174513-82-7 (3aS,5S,6R,6aS)-2,2,6-Trimethyl-tetrahydro-furo[2,3-d][1,3]dioxole-5-carbaldehyde 

Relevant academic research and scientific papers

Total synthesis of bafilomycin A1. 1. Syntheses of the C5~C11, C12~C17 and C18~C25 segments

The effective syntheses of the C5~C11 (2), C12~C17 (3) and C18~C25 (4) segments, which are promising synthetic intermediates toward the total synthesis of the macrolide antibiotic, bafilomycin A1 (1), were described.