174456-85-0Relevant academic research and scientific papers
Bicyclo[3,1,0]hexane containing oxazolidinone antibioytics and derivatives thereof
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, (2008/06/13)
Oxazolidinones having a bicyclic[3.1.0] hexane containing moiety, which are effective against aerobic and anerobic pathogens such as multi-resistant staphylococci, streptococci and enterococci, Bacteroides spp., Clostridia spp. species, as well as acid-fa
Pyrrolidine modulators of CCR5 chemokine receptor activity
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, (2008/06/13)
Pyrrolidine compounds of Formula I: (wherein 1, R2, R3, R4, R5,R6a, R6b, R7 and R8 are defined herein) are described. The compounds are modulators of CCR5 chemokine receptor activity. The compounds are useful, for example, in the prevention or treatment of infection by HIV and the treatment of AIDS, as compounds or pharmaceutically acceptable salts, or as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
Aza bicyclo[3,1,0]hexane intermediates useful in the synthesis of quinolones
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, (2008/06/13)
This invention relates to certain azabicyclo hexane intermediates and processes for making and using the azabicyclo hexane intermediates. The intermediates are useful in the synthesis of quinolone antibacterial agents.
