174467-64-2Relevant academic research and scientific papers
Synthesis of substituted 2H-benzo[e]indazole-9-carboxylate as a potent antihyperglycemic agent that may act through IRS-1, Akt and GSK-3β pathways
Taneja, Gaurav,Gupta, Chandra Prakash,Mishra, Shachi,Srivastava, Rohit,Rahuja, Neha,Rawat, Arun Kumar,Pandey, Jyotsana,Gupta, Anand P.,Jaiswal, Natasha,Gayen, Jiaur R.,Tamrakar, Akhilesh K.,Srivastava, Arvind Kumar,Goel, Atul
, p. 329 - 337 (2017/03/08)
Based on high throughput screening of our chemical library, we identified two 4,5-dihydro-2H-benzo[e]indazole derivatives (5d and 5g), which displayed a significant effect on glucose uptake in L6 skeletal muscle cells. Based on these lead molecules, a ser
Substituent directed regioselective synthesis of 2-oxonicotonic acids and methyl nicotinates
Pratap, Ramendra,Farahanullah,Raghunandan, Resmi,Maulik,Ram, Vishnu Ji
, p. 4939 - 4942 (2008/02/08)
An innovative synthesis of aryl tethered 1,2-dihydro-2-oxopyridine-3-carboxylic acids has been developed through nucleophile induced ring transformation of methyl 6-aryl-4-methylsulfanyl-2H-pyran-2-one-3-carboxylates using either cyanamide or arylamidine
Functionalized 1,3-teraryls as a new class of hepatoprotectants: Part V
Ram, Vishnu J.,Goel, Atul,Patnaik
, p. 469 - 472 (2007/10/03)
Functionalized 1,3-teraryls, synthesized through ring transformation of 6-aryl-3-carbomethoxy-4-methylthio-2H-pyran-2-one from arylketone have been screened for their hepatoprotective activity and some of them have demonstrated significant protection in animal model.
