174469-08-0

Upstream product

• 152560-63-9 2-chloro-3-(oxiranylmethoxy)-pyridine 
• 98-59-9 p-toluenesulfonyl chloride 
• 174469-04-6 (7-chloro-2,3-dihydrofuro<2,3-c>pyridine-3-yl)methanol 

Downstream Products

• 174469-13-7 4-(4-fluorobenzoyl)-1-(7-chloro-2,3-dihydrofuro<2,3-c>pyridin-3-ylmethyl)piperidine 
• 174469-12-6 8-(7-chloro-2,3-dihydrofuro<2,3-c>pyridin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro<4,5>decan-4-one 

Relevant academic research and scientific papers

SYNTHESIS OF N-SUBSTITUTED 3-AMINOMETHYL-2,3-DIHYDROFUROPYRIDINES, POTENT SEROTONINERGIC LIGANDS

Regioselective lithiation of 2-chloro-3-oxiranylmethoxypyridine, followed by intramolecular epoxide ring-opening reaction provided (7-chloro-2,3-dihydrofuropyridin-3-yl>methanol (1).Multistep synthesis from 1 gave a variety of N-substituted 3-amino