174485-45-1

Upstream product

• 1026984-25-7 C₁₀H₁₆O₃ 
• 99395-88-7 (S)-4-phenyl-2-oxazolidinone 
• 33698-85-0 (E)-pent-2-enoyl chloride 
• 13991-37-2 trans-2-pentenoic acid 

Downstream Products

• 1197006-84-0 (2'S,2R,3S,4S)-{[3,4-dihydro-4-ethyl-2-(4-nitrophenyl)-5-phenyl-2H-pyrrol-3-yl]-carbonyl}-2-oxo-4-phenyloxazolidine 
• 221044-26-4 (4S)-4-phenyl-3-<(3R)-3-phenylpentanoyl>-1,3-oxazolidin-2-one 
• 99395-88-7 (S)-4-phenyl-2-oxazolidinone 

Relevant academic research and scientific papers

Dihydropyrazole GPR40 modulators

The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.

Substituted n-pentanamide compounds, preparation method and the use thereof

The present invention relates to a (2R, 3R)-3-(3-substituted phenyl)-2-methyl n-pentanamide compounds as shown in the formula I and the preparation method thereof, wherein, the substituents are as defined in the specification, the present invention further relates to a use of the above compounds for the preparation of tapentadol II or its pharmaceutically acceptable salt, and the intermediates involved in the preparation process.

SUBSTITUTED N-PENTANAMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF

The present invention relates to a (2R, 3R)-3-(3-substituted phenyl)-2-methyl n-pentanamide compounds as shown in the formula I and the preparation method thereof, wherein, the substituents are as defined in the specification, the present invention further relates to a use of the above compounds for the preparation of tapentadol II or its pharmaceutically acceptable salt, and the intermediates involved in the preparation process.