1745-12-6

Basic information

• Product Name: 6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline; picrate
• CAS NO: 1745-12-6
• Molecular Weight: 422.351
• Mol File: 1745-12-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline; picrate(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline; picrate(1745-12-6)
• EPA Substance Registry System: 6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline; picrate(1745-12-6)

Safety Data

• Hazardous Substances Data: 1745-12-6(Hazardous Substances Data)

Upstream product

• 1745-07-9 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 88-89-1 2,4,6-Trinitrophenol 
• 111875-03-7 N-(3,4-dichlorobenzylsulfonyl)-6,7-dimetoxy-1,2,3,4-tetrahydroisoquinoline 
• 111874-92-1 C-(3,4-Dichloro-phenyl)-N-[2-(3,4-dimethoxy-phenyl)-ethyl]-methanesulfonamide 
• 111875-04-8 3-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinoline-2-sulfonyl)-propionic acid ethyl ester 
• 111874-93-2 3-[2-(3,4-Dimethoxy-phenyl)-ethylsulfamoyl]-propionic acid ethyl ester 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 

Relevant articles and documents

Synthesis of Fused Heterocycles: 1,2,3,4-Tetrahydroisoquinolines and Ring Homologues via Sulphonamidomethylation

The title heterocycles (3) have been obtained by a two-step synthesis; namely an initial intramolecular sulphonamidomethylation of N-aralkylsulphonamides (1) in acid media followed by desulphonylation of compounds (2) under moderate conditions, either by reduction or acid hydrolysis.Generally both steps gave good or high yields of compounds (3) variously substituted in the aromatic ring and with a six-, seven-, or eight-membered heterocyclic ring.