174504-14-4

Basic information

• Product Name: (3R,4S,5R,6R)-1-Allyl-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-2-one
• Synonyms: (3R,4S,5R,6R)-1-Allyl-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-2-one
• CAS NO: 174504-14-4
• Molecular Weight: 577.72
• Mol File: 174504-14-4.mol

Chemical Properties

• CAS DataBase Reference: (3R,4S,5R,6R)-1-Allyl-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4S,5R,6R)-1-Allyl-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-2-one(174504-14-4)
• EPA Substance Registry System: (3R,4S,5R,6R)-1-Allyl-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-2-one(174504-14-4)

Safety Data

• Hazardous Substances Data: 174504-14-4(Hazardous Substances Data)

Upstream product

• 77174-08-4 (3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)piperidin-2-one 
• 106-95-6 allyl bromide 

Downstream Products

• 174591-18-5 (3aR,3bS,4R,5S,6R,8aS)-4,5,6-Tris-benzyloxy-2,2-dioxo-hexahydro-1,3-dioxa-2λ⁶-thia-7a-aza-cyclopenta[a]inden-7-one 
• 174504-17-7 (E)-3-((2R,3R,4S,5R)-1-Allyl-3,4,5-tris-benzyloxy-6-oxo-piperidin-2-yl)-acrylic acid methyl ester 
• 174504-16-6 (2S,3R,4S,5R)-1-Allyl-3,4,5-tris-benzyloxy-6-oxo-piperidine-2-carbaldehyde 
• 174504-15-5 (3R,4S,5R,6R)-1-Allyl-3,4,5-tris-benzyloxy-6-hydroxymethyl-piperidin-2-one 
• 174504-18-8 (6R,7S,8R,8aR)-6,7,8-Tris-benzyloxy-6,7,8,8a-tetrahydro-3H-indolizin-5-one 
• 129390-68-7 (1S,6R,7S,8R,8aR)-1-hydroxy-6,7,8-tris(benzyloxy)indolizidin-5-one 
• 79831-76-8 (1S,6S,7R,8R,8aR)-2,6,7,8-tetrahydroxy-indolizidine 

Relevant articles and documents

A formal synthesis of castanospermine using an olefin metathesis cyclisation reaction as a key step

The formal synthesis of castanospermine (1) starting from tetrabenzylgluconolactam (3) is described. Olefin metathesis cyclisation reaction of dialkene 9, derived from 3, leads to indolizidinone 10, which can be used as a key intermediate for the synthesis of castanospermine (1) and its analogues.