17451-38-6

Basic information

• Product Name: N,N'-dibenzylethylmalonamide
• Synonyms: N,N'-dibenzylethylmalonamide
• CAS NO: 17451-38-6
• Molecular Weight: 310.396
• Mol File: 17451-38-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N'-dibenzylethylmalonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-dibenzylethylmalonamide(17451-38-6)
• EPA Substance Registry System: N,N'-dibenzylethylmalonamide(17451-38-6)

Safety Data

• Hazardous Substances Data: 17451-38-6(Hazardous Substances Data)

Upstream product

• 15781-72-3 bis(2,4,6-trichlorophenyl) ethylmalonate 
• 91265-82-6 C₁₀H₁₂N₂O₂S 
• 100-46-9 benzylamine 
• 26717-67-9 dimethyl ethylmalonate 
• 133-13-1 ethyl diethyl malonate 

Relevant articles and documents

Studies of Amine-Induced Ring Opening of Some Mesoionic Xanthines

The ring-opening reactions of seven mesoionic thiazolopyrimidine-5,7-diones by a series of primary and secondary amines have been investigated.The rates of the ring fission of five N(8)-substituted mesoionic xanthines with benzylamine were measured and found to follow second order kinetics.The Hammett relationship is followed with ρ value of +0.48 in p-dioxane as solvent.The dependence of rates on temperatures has been studied for the N(8)-ethyl derivative; the energy of activation (ΔE*) is 25.3 kcals mol-1, the enthalpy of activation (ΔH*) is 24.7 kcals mo l -1 and the entropy of activation (ΔS*) is -4.9 e.u.A slight increase in rate of reaction was observed when the solvent was changed from p-dioxane to dimethyl sulfoxide.In p-dioxane at constant mesoionic xanthine concentration, the rate constant for ring opening decreased with increasing benzylamine concentration.These results are consistent with a bimolecular nucleophilic mechanism proceeding by the rate-determining formation of a charged tetrahedral transition state.